qnrD is a plasmid mediated quinolone resistance gene from unknown origin, recently described in Enterobacteriaceae. It encodes a pentapeptide repeat protein 36-60% different from the other Qnr (A, B, C, S and VC). Since most qnrD-positive strains were described as strains belonging to Proteus or Providencia genera, we hypothesized that qnrD originated in Proteeae before disseminating to other e...

Cefotaxime, a new semisynthetic cephalosporin derivative, showed a broad spectrum of antibacterial activity against clinically isolated strains of gram-positive and gram-negative bacteria. This cephalosporin was slightly less active than cefazolin against Staphylococcus aureus but 4 to 300 times as active as carbenicillin against gram-negative organisms, including Pseudomonas aeruginosa, Pseudo...

The juices of leaves and stem of Mentha piperita (peppermint), skin and seeds of Pisum sativum (garden pea), skin and pulp of Momordica charantia (bitter melon) were screened for antibacterial activities against 56 isolates belonging to 11 different species of Gram-negative bacilli: Escherichia coli (19), Klebsiella pneumoniae (11), Pseudomonas aeruginosa (9), Salmonella typhi (3), Salmonella p...

Bacterial urease, particularly from Proteus mirabilis, has been implicated as a contributing factor in the formation of urinary and kidney stones, obstruction of urinary catheters, and pyelonephritis. Weekly urine specimens (n = 1,135) from 32 patients, residing at two chronic-care facilities, with urinary catheters in place for greater than or equal to 30 days yielded 5,088 phenotypically and ...

In searching for evidence in favor of the etiological significance b. proteus vulgaris x19 typhus and on assumption that patients must be hypersensitive to this microbe, Prof. Friedberger together with Dr. Reis 1919 applied subcutaneous (and also intradermal) administration suspensions killed bacilli prot. x19. expected when certain doses suspension, which were completely indifferent healthy pe...

Bioactivity of thyme has been described, but mostly related to its essential oils, while studies with aqueous extracts are scarce. Herein, the antioxidant and antibacterial properties of decoction, infusion and hydroalcoholic extract, as also their phenolic compounds, were evaluated and compared. Decoction showed the highest concentration of phenolic compounds (either phenolic acids or flavonoi...