Abstract Background Wound healing is impaired in patients with diabetes due to the multifactorial etiology of disease, which limits therapeutic efficacy various approaches. This study hypothesizes that combination adipose-derived stem cells (ADSCs) and platelet-rich plasma (PRP) might achieve optimally efficient diabetic wound healing. Methods ADSCs were isolated from adipose tissues Sprague-Da...

BACKGROUND It is still not clear whether native or platelet count adjusted platelet rich plasma (PRP) should be used for platelet aggregation measurements. AIM To evaluate the necessity of using adjusted PRP in platelet function testing. METHODS Platelet aggregation with native PRP and adjusted PRP (platelet count: 250/nl, obtained by diluting native PRP with platelet poor plasma) was perfo...

BACKGROUND Clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. The aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (PRP) injection in healing Achilles tendons of rats. METHODS Forty rats were randomly divided into 5 equal groups. Se...

BACKGROUND After anterior cruciate ligament (ACL) reconstruction, formation of cortical sclerotic bone encircling the femoral and tibial tunnel is a part of intratunnel graft healing. During the physiological cascades of soft tissue healing and bone growth, cellular and hormonal factors play an important role. The purpose of this study was to non-invasively but quantitatively assess the effect ...

Platelet Rich Plasma contains a major Growth factor and has adhesive healing properties. PRP promotes angiogenesis, collagen synthesis, wound healing. The main aim of this study is to compare the efficacy SSG fixation using autologous platelet-rich plasma with conventional method like suturing. In study, patients who were admitted diagnosis ”ulcer” in General Surgery department SRM medical coll...

An important reason to improve methods of isolating platelet-rich plasma (PRP) is the potential use of autologous platelet growth factors. In addition to discontinuous plasma separation, a second method for extraction of PRP has now become available, which can be performed directly by the surgeon. In this study, the suitability of the 2 methods of producing PRP was compared. Whole blood was dra...

Introduction: In orthopedics, the use of rich plasma is still controversial, there no consensus regarding its indications, and use, although therapeutic usefulness for various conditions proven, much remains to be studied on this promising topic. Purpose: With our study we intend assess clinical effectiveness efficacy treatment imposed according groups. Method. A prospective pre-experimental wa...

Abstract Introduction Platelet-rich plasma (PRP) has gathered great momentum in surgery. The main outcome of the study was to assess whether there a difference growth factor release from PRP with addition vitamin C, cooling, or both C and cooling. Method Blood samples 10 volunteers were centrifuged produce PRP. Activated autologous thrombin produced platelet-poor (PPP), which added activate it....