نتایج جستجو برای: psoriasis vulgaris
تعداد نتایج: 41889 فیلتر نتایج به سال:
BACKGROUND Psoriasis is a disease of worldwide distribution with a prevalence of 1 to 3%. Nail psoriasis is estimated in 50% of patients with psoriasis, and in the presence of joint involvement, it can reach 80%. OBJECTIVE To study the nail changes - and their clinical implications - presented by patients with psoriasis vulgaris under surveillance in a university hospital from the south of Br...
Objective: To explore the expression and clinical significance of miR-155 miR-146a in psoriasis patients from different sources. Methods: The levels vulgaris tissues, peripheral blood mononuclear cells, serum were detected by QRT-PCR method 30 with healthy subjects as normal control group, correlation between samples sources was analyzed. And after treatment. Results: skin tissue, cells signifi...
Caspase recruitment family member 14 (CARD14, also known as CARMA2), is a scaffold protein that mediates NF-κB signal transduction in skin keratinocytes. Gain-of-function CARD14 mutations have been documented in familial forms of psoriasis vulgaris (PV) and pityriasis rubra pilaris (PRP). More recent investigations have also implicated CARD14 in the pathogenesis of pustular psoriasis. Follow-up...
Circulating T follicular helper (cTfh) cells are known to be involved in numerous immune-mediated diseases, but their pathological role in psoriasis is less fully investigated. Herein, we aimed to identify whether cTfh cells contributed to the pathogenesis of psoriasis. The frequency and function of cTfh cells were compared between patients with psoriasis vulgaris and healthy controls, and the ...
Psoriasis vulgaris is a complex, inflammatory skin disease of the skin affecting 2% of Western populations. Genetic linkage analysis with extended U.S. and Italian families and gene expression studies implicate genetic variation at 1q21 (PSORS4) in conferring psoriasis susceptibility. A 2.5 Mb region on 1q21 harbors the gene rich Epidermal Differentiation Complex (EDC), whose genes have importa...
Die generalisierte pustuläre Psoriasis (GPP) ist eine schwere und potenziell lebensbedrohliche Art der Psoriasis. Wir stellen den Fall eines Patienten mit schwerer GPP vor, die zunächst erfolglos Cyclosporin behandelt wurde. haben uns für Behandlung des Ixekizumab entschieden, einem Anti-IL-17-Antikörper, seine schnelle Wirkung bei vulgaris bekannt auch als wirksam beschrieben Der Zustand verbe...
OBJECTIVE To determine the frequency of anxiety and depression in patients with psoriasis. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Outpatient Departments of Dermatology and Psychiatry, Ziauddin University Hospital, KDLB Campus, Karachi, from October 2005 to September 2006. PATIENTS AND METHODS All patients presenting with psoriasis vulgaris above the age of 15 year...
BACKGROUND Psoriasis, a common cutaneous disorder characterized by inflammation and abnormal epidermal proliferation with a prevalence of 2-3% in the general population, may be linked to certain types of cancer. Several studies have reported an association between interleukin 10 (IL-10) variant polymorphisms and inflammatory diseases such as psoriasis vulgaris although the results vary accordin...
Psoriasis is a common chronic skin disorder characterized by abnormal epidermal proliferation and infiltration of inflammatory cells which affects approximately 2-4 % of the general population [1-3]. Psoriasis Vulgaris (PV), the most common clinical variant, comprises 85 to 90% of all patients with psoriasis. This disease is usually manifested as well-demarcated erythematous oval plaques with s...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید