OBJECTIVE Elderly patients prefer to receive less-toxic therapy. Monotherapy using drugs such as vinorelbine, gemcitabine or docetaxel is a preferable chemotherapy in elderly patients with advanced non-small-cell lung cancer. Gefitinib shows remarkable efficacy in patients with advanced non-small-cell lung cancer, who have activating epidermal growth factor receptor mutations. Adenocarcinoma hi...

We report a rare case of metastatic non-small-cell lung cancer in a 43-year-old woman with a history of smoking. The tumor secreted human chorionic gonadotropin and its beta subunit (BetaHCG). The patient presented with amenorrhea, a positive pregnancy test and chest pain. A physical examination and investigations revealed no pregnancy, and it was determined that a paraneoplastic syndrome stemm...

OBJECTIVE Metastatic tumors of the mandible are rare and usually present clinically as growths. The prognosis of lung cancer patients with bone metastases is poor. CASE REPORT This article shows a metastasis from adenocarcinoma of the lung affecting the mandible of a 75-year-old female patient where the metastatic lesion was detected before primary tumor. The patient were treated with radiati...

INTRODUCTION Henoch-Schönlein purpura is a common immunoglobulin A-mediated vasculitis syndrome in children. Henoch-Schönlein purpura can also affect adults and is probably related to malignancy. CASE PRESENTATION We report the case of a 61-year-old Japanese man who presented for examination after an abnormal shadow was detected by chest radiography. He received a diagnosis of pulmonary adeno...

positron emission tomography (FDG-PET)/CT scan for staging demonstrated hypermetabolic FDG uptake in the lung mass (figure 1A) and an unexpectedly focal FDG uptake in the left paraspinal muscle (figure 1B). Physical examination was normal. Biopsy from the muscle showed infiltration with cells of adenocarcinoma. A revision of the initial CT scan revealed a mass in the left paraspinal muscle whic...

We recommend Lin et al. (1) for their interesting article on a case of atypical pulmonary metastases from carcinosarcoma of the parotid gland, demonstrating the radiologic features of an air-space pattern and calcification. We concur with their study in considering this type of lesions a formidable diagnostic challenge in the patients with unknown extrapulmonary malignancies. We would like to l...

This report, based on data from a clinical case, proposes that pulmonary tumor thrombotic microangiopathy, an underdiagnosed cause of pulmonary hypertension and death in patients with adenocarcinoma, is a paraneoplastic syndrome (PNS). Clinicians in general must be alert to the presence or development of PNS that may precede, coincide with, follow, or herald the recurrence or the primary diagno...

A 60 year old male with a long standing history of smoking was referred to our department for surgery of aspergilloma in right upper lung lobe diagnosed by computed tomography and confirmed by computed tomography guided needle aspiration biopsy. A lobectomy was performed. Histological study of the surgical specimen revealed a pulmonary adenocarcinoma associated with aspergilloma. By presenting ...

pISSN 2383-7837 eISSN 2383-7845 © 2015 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work...

A 65-year-old woman visited our department due to the presence of a dry cough. On auscultation, crackles were heard predominantly in both lung bases. Chest radiography showed bilateral nodular opacities (Picture 1). Chest computed tomography showed nodules, cysts, pseudocavitations (arrowheads), and masses with cavities (Picture 2). Although septic emboli, tuberculosis, fungal infection, and cy...