The electrocardiograms in 32 patients with mitral valve disease have been compared with the pulmonary resistances, the pulmonary artery pressures, and the size of the mitral valve orifice. In patients with pure stenosis if the electrocardiogram showed the pattern of right ventricular hyper-trophy the total pulmonary resistance was usually 1000 dynes seconds cm.-5 or greater. If mitral insuffici...

A 9-year-old girl with the supravalvar aortic stenosis syndrome is presented. In addition to the classical features of the syndrome, namely supravalvar aortic stenosis, peripheral pulmonary stenosis, typical facies, and mental retardation, she was also found to have stenosis at the origin of all aortic arch main branches, a hitherto undescribed feature.

The arterial switch operation (Jatene procedure) is the treatment of choice for transposition of the great arteries with intact ventricular septum (TGA-IVS) in neonatal age, because of the low mortality and morbidity during long term follow up. Right ventricular outflow obstruction is the most frequent postoperative complication, occurring with suYcient severity to require reintervention in up ...

BACKGROUND Pulmonary tumor thrombotic microangiopathy (PTTM) has been known as a rare and serious cancer-related pulmonary complication. However, the pathogenesis and pathophysiology of this debilitating condition still remains obscure and no effective management was recommended. The present study aims to elucidate the pathophysiology of PTTM. METHODS Autopsy records were searched to extract ...

A clinical and phonocardiographic study has been made of the murmurs and heart sounds in the differentiation of Fallot's tetralogy from severe pulmonary stenosis with intact septum and right-to-left interatrial shunt. A striking difference in the behaviour of the systolic mnurlmur was found in the two conditions and this affords a new, simple bedside method of diagnosis. Important differences i...

A caucasian teenage Dutch schoolgirl with known chronic low visual acuity and albinism, presented with frank acute pulmonary oedema, died after 1 h of cardio-pulmonary resuscitation for bradyarrhythmia and cardiac arrest. Two weeks prior to presentation, during sport training, she complained of oppressive chest pain on exertion accompanied with vomiting without any other systemic symptoms. Post...

PERIPHERAL pulmonary artery stenosis is being recognized with increasing frequency.1-3 Several observers4-6 have stressed the presence of a continuous murmur as a diagnostic feature, and continuous murmurs have been experimentally produced by graded constriction of a large branch of the pulmonary artery in dogs.5 This is the case report of an infant with severe multiple peripheral pulmonary art...