Pulse wave patterns were analysed in 10 term and 10 preterm infants with patent ductus arteriosus (PDA) and in 2 matched control groups. A non-invasive technique was used to record the pulse waves from the axillary artery. The pulsatile ratio was calculated as the quotient between the amplitude of the incisural notch and the peak of the pulse wave above the end diastolic baseline. The pulsatile...

INTRODUCTION In clinical practice, extracorporeal circulation (ECC) is normally performed with non-pulsatile flow by means of centrifugal or roller pumps, which makes it rather non-physiological for patients [1-3]. Currently used circuits are quite voluminous, characterized by large priming volumes and by extended blood contact with foreign surfaces. We have previously proposed an innovative EC...

The cardiovascular disease is one of most frequent cause deaths in modern society. The objective of this work is analyse the effect of dynamic vascular geometry (curvature, torsion, bifurcation) and pulsatile blood nature on secondary flow, wall shear stress and platelet deposition. The problem was examined as multi-scale physical phenomena using perturbation analysis and numerical modelling. T...

The purpose of this study was to contrast the effects of static and pulsatile pressure on carotid baroreceptor activity over a wide range of mean arterial pressure. Static and pulsatile pressure were applied to the isolated carotid sinus of dogs anesthetized with chloralose. Recordings were obtained from single baroreceptor units as well as from the whole sinus nerve or a large strand of the ne...

Computational models of cerebral aneurysm thrombosis are designed for use in research and clinical applications. A steady flow assumption is applied many these models. To explore the accuracy this a pulsatile-flow thrombin-transport computational fluid dynamics (CFD) model, which uses symmetrical idealized geometry, was developed. First, steady-flow model developed validated using data from an ...

LH release in response to pulsatile administration of small amounts of GnRH analogue in cows with follicular cysts was examined. The pulsatile administration of GnRH analogue induced a LH-surge like peak over 10 hr in both normal cows and cows with follicular cysts. The mean peak value of LH in follicular cystic cows did not differ significantly from that of normal cows. All the cows with cysts...

Neurofibromatosis type 1 (NF-1) is a neurocutaneous syndrome with multisystem involvement, especially the central nervous system, eyes, and skin. In this article, we describe a patient with NF-1 with radiologically-imaged sphenoid wing aplasia that led to pulsatile enophthalmos. Although sphenoid wing aplasia in patients with NF-1 frequently occurs as painless pulsatile exophthalmos in clinical...

The cervical course of the internal carotid artery is almost straight in contrast to the intracranial portions which are highly tortuous. The incidence of variations in the cervical course of the internal carotid artery of the population is approximately 10-40 percent. In this case report, a 76-year-old female patient with a pulsatile mass at the posterior oropharyngeal wall and anterior neck w...

Bistability in periodically paced cardiac tissue is relevant to cardiac arrhythmias and its control. In the present paper, one-dimensional tissue of the phase I Luo-Rudy model is numerically investigated. The effects of various parameters of pacing signals on bistability width are studied. The following conclusions are obtained: (i) Pacing can be classified into two types: pulsatile and sinusoi...

The ability to deliver therapeutic agents to a patient in a pulsatile or staggered release profi le has been a major goal in drug delivery research recently. This review will cover methods that have been developed to control drug delivery profi le with different polymeric systems. Externally and internally controlled systems will be considered, including a range of technologies like preprogramm...