Uncertainty in arterial input function (AIF) estimation is one of the major errors in the quantification of dynamic contrast-enhanced MRI. A blind source separation algorithm was proposed to determine the AIF by selecting the voxel time course with maximum purity, which represents a minimal contamination from partial volume effects. Simulations were performed to assess the partial volume effect...

Various materials that are used for vascular and heart valve prostheses carry drawbacks: some require anticoagulant drugs or have moderate durability; others are not suitable for endovascular treatment. These prostheses are associated with bacterial infections. A material potentially suitable for prostheses is Dyneema Purity®, made of ultra-high-molecular-weight polyethylene. Dyneema Purity® fi...

Optimal recovery of nucleic acids from formalin-fixed paraffin-embedded (FFPE) tissues is highly dependent on a series of pre-extraction steps, mainly related (but not limited) to fixation. The aim of our study was to investigate if the storage period of the FFPE blocks had a significant effect on the isolated DNA. We examined the quantity and purity of the isolated DNA from 83 FFPE blocks, cor...

The preparation of stable amorphous pemetrexed disodium of pharmaceutical purity as well as the process optimization for the preparation of the hemipentahydrate form of pemetrexed disodium are described. Analytical methods for the polymorphic and chemical purity studies of pemetrexed disodium and pemetrexed diacid forms were developed. The physicochemical properties of the amorphous and hydrate...

Antithrombin (AT) is a glycoprotein that inactivates the several physiological target enzymes of coagulation system. The effect of purification strategies plays a crucial role in getting maximum recovery of yield, purity and biological activity of recombinant human antithrombin (rhAT). In the present work, the task of purifying rhAT from Saccharomyces cerevisiae BY4741 has been carried out usin...

We propose a novel integrated scheme for generation of Bell states, which allows simultaneous spatial filtering of pump photons. It is achieved through spontaneous parametric down-conversion in the system of nonlinear adiabatically coupled waveguides. We perform detailed analytic study of photon-pair generation in coupled waveguides and reveal the optimal conditions for the generation of each p...

This study aims to derive context-based lighting setup presets in residential space by exploring the multilateral relationships among household activities, affects, and lighting setups. Three procedures were involved: First, sixty affective words were evaluated through which seven affect factors were extracted to facilitate the evaluation of colored illumination in the subsequent experiment. Se...

Sucrose concentration of sugarbeets (Beta vulgaris L.) grown in the U.S. varies over a wide range of 10 to 20 percent. Within a climatic zone such as tration varies over a narrower 20 percent. This variation in southern Idaho, sucrose concenbut still wide range of 14 to sucrose concentration is due to many factors that include variety (19, 24, 26), nitrogen (N) level (18, 23), growth patterns o...