Erythromycin overcomes postvagotomy gastroparesia in patients without a distal stomach and functional pylorus. We investigate the role of the vagus in gastric emptying increased by erythromycin, using a model that preserves the physiology of the distal stomach and pylorus. The effects of erythromycin lactobionate (10 mg/kg) on transpyloric flow pattern and pyloric resistance were evaluated duri...

Water, methanol and chloroform extracts of Landolphia owarensis were investigated for their effects on gastric acid secretion and ulceration in male albino rats. Two models of gastric lesion induced in experimental Wistar rats-HC1/ethanol-induced gastric lesions and Pylorus ligation-induced gastric lesions-were employed. In both models, the antiulcer activity of LA was compared with that of cim...

The objective of present study is to evaluate the antiulcer activity of ethanolic extract of flower of Azadirachta indica. The cause of ulceration in patients is mainly due to hyper secretion of gastric acid and pepsin. Plant extracts and polyherbal formulations are some of the most attractive sources of new drugs and have been shown to produce promising results in the treatment of gastric ulce...

The objective of the present study was to investigate and compare the antiulcer effect of potassium channel openers, nicorandil and levcromakalim in the models of ulcer induced by pylorus ligation, aspirin and water immersion plus restraint stress in albino rats. Levcromakalim (250 g/kg) and nicorandil (10 mg/kg) were administered intraduodenally immediately after pylorus ligation. Ulcer index ...

Gastric carcinoma is extremely rare in children representing only 0.05% of all gastrointestinal malignancies. Here, we report the first pediatric case of gastric cancer presenting with gastric outlet obstruction. Upper endoscopy revealed a markedly thickened antral mucosa occluding the pylorus and a clean base ulcer 1.5 cm × 2 cm at the lesser curvature of the stomach. The narrowed antrum and p...

INTRODUCTION Billroth gastrectomy has some advantages of inhibiting acid secretion, low ulcer recurrence and low mortality. However, postoperative complications, such as dumping syndrome and reflux gastritis, often occurred as a result of pylorectomy. To minimize these complications, pylorus-preserving gastrecto my (PPG) had been performed for gastric ulcer with satisfied clinical results. P os...

Ficus religiosa is being used in Ayurvedic and Malay traditional medicine for the treatment of various diseases including gastric ulcer. Considering the above claims, the present work was undertaken to validate the anti-ulcer potential of the ethanol extract of leaves of Ficus religiosa against in vivo aspirin induced ulcer and pylorus ligation assays. Gastric ulcers induced in Swiss albino rat...

OBJECTIVES The objective was to evaluate the accuracy of pediatric emergency physician (EP) sonography for infants with suspected hypertrophic pyloric stenosis (HPS). METHODS This was a prospective observational pilot study in an urban academic pediatric emergency department (PED). Patients were selected if the treating physician ordered an ultrasound (US) in the department of radiology for t...

Pylorus-preserving pancreatoduodenectomy has become a standard operation for distal and middle bile duct cancers. Bile duct cancer typically extends longitudinally and invades vertically. It frequently metastasizes to the lymph nodes and infiltrates the perineural spaces. The presence of residual cancer in the bile duct stump and lymph node metastases are significant prognostic factors. Negativ...

OBJECTIVE To evaluate risk factors for gallstones after gastrectomy. METHODS To identify documents published from 1990 to 2011 the Pubmed, Cochrane Library, Springer Link, CBM and WanFang databases were searched and a meta-analysis was performed with RevMan 5.2 software for odds ratios and 95%CIs. RESULTS Fifteen studies were selected for the meta-analysis. The pooled ORs [95%CIs] were 0.56...