A phytochemical investigation of Ficus virens leaves led to isolation of six flavonoids (1–6). On the basis of 2D and/or 1D NMR, and mass data, together with the comparison with the literature values, the flavonoids were identified as quercetin (1), quercetin-3-O-α-D-arabinopyranoside (2), quercetin-3-O-β-Dgalactopyranoside (3), kaempferol-3-O-α-D-arabinopyranoside (4), kaempferol-3-O-β-Dgalact...

Quercetin and gallic acid are natural activators of the transcription factor Nrf2, which regulates the expression of many cytoprotective enzymes including heme oxygenase-1 (HO-1). We developed procedures for the synthesis of monogalloyl esters of quercetin and taxifolin (dihydroquercetin), namely, 3-O-galloylquercetin and 7-O-galloyltaxifolin, and examined their effect on the Nrf2 pathway in RA...

OBJECTIVE Mast cells are involved in allergic and inflammatory reactions. These cells are also increased in the bone marrow, skin, and other organs in systemic mastocytosis. Flavonoids are naturally occurring molecules with antioxidant, cytoprotective, and anti-inflammatory activities. Some flavonoids, like quercetin, inhibit the growth of certain malignant cells in culture. Quercetin also inhi...

introduction: lead is one of the most important environmental pollutants due to its vast use in various industries. lead accumulation in different organs, especially the brain, liver and kidneys can cause serious health problems. lead exposure is more dangerous during fetal period and childhood. materials and methods: timed pregnant female rats divided into 6 groups. group 1served as control gr...

AIM: To identify the chemical constituents in Cuscuta Chinensis. METHODS: A High-performance liquid chromatography (HPLC) method combined with quadrupole-time-of-flight-mass spectrometry (QTOF-MS) has been developed for precise separation and structural identification of components in Cuscuta Chinensis. Mass spectrometry was performed in reflective time-of-flight using electron spraying ionizat...

In recent years, there is an increasing interest in antioxidants. The main reason for this interest is the protection of cells, their organelles (especially membranes) and metabolic pathways against oxygen free radicals and their reactive derivatives (ROS). They participate in formation of chronic inflammation states and other diseases associated with oxidative stress, such as cancer, hypertens...

The flavonoid quercetin, or its metabolites, inhibit chemical carcinogenesis in rodents and may have a role in the prevention of human cancers. Quercetin exposure in human populations results from the dietary intake of various plant foods; high concentrations of quercetin are found in apples, onions, tea, and red wine. Determination of the relationship between dietary intake and cancer risk dep...

The non-anthocyanin phenolic compounds in wines from five grape cultivars (Zuo Shan Yi, Zuo Shan Er, Shuang Hong, Shuang You and Shuang Feng) of Vitis amurensis and two hybrid cultivars (Zuo Hong Yi and Zuo You Hong) were examined by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS) technique in this study. The non-anthocyanin phenolic comp...