Background: This study aimed to evaluate the reaction of organism of laboratory animals on deuterium-depleted drinking diet. To assess the cell energy metabolism, the effect of a liquid medium with different deuterium contents on isolated liver mitochondria of random bred rats and Wistar rats was studied. Methods: This experimental study on the effect of deuterium-depleted drinking water (DDW) ...

BACKGROUND The effect of feeding a limited iodine diet on radioactive iodine uptake in the thyroid glands of hyperthyroid cats is unknown. OBJECTIVES To determine how feeding limited dietary iodine affects radioactive iodine uptake by the thyroid glands of hyperthyroid cats. ANIMALS Eight geriatric cats with spontaneous hyperthyroidism. METHODS Prospective study of eight client owned hype...

of cancer with the hope of developing useful diag nostic and therapeutics agents. The aim in such investigations has been to find a dye which, in the intact animal, stains living tumor cells without staining surrounding tissue. A large number of acid dyes, especially in the azo series, has been rather intensively investigated for such a purpose. From these investigations there has resulted gen ...

A charge state breeder, which transforms externally injected singly charged ions to a higher charge state q+, is an important tool which has applications within atomic, nuclear and even particle physics. The charge breeding concept of radioactive ions has already been demonstrated at REX-ISOLDE/CERN with the use of an Electron beam Ion Source (EBIS) and at several facilities employing Electron ...

T he last half century has seen great progress in environmental health protection. As part of this progress there has been a growing awareness that the focus must be the protection of those most at risk. The protection of children, in particular, has grown significantly in prominence. In the United States for example, There has also been a great deal of progress in radiation protection .known a...

In normal and lathyritic chick embryos bone collagen was synthesized primarily in the periosteum of the femurs, and was organized as radioactive spicules in these bones. Saline extraction of the lathyritic bones removed the radioactive spicules, although they eventually seemed to become non-extractable. Normal bone seemed to be unaffected by saline extraction. Marked variation in the degree of ...

In the course of carrying out sterol balance studies in 19 patients, we gathered the following evidence that, in some but not all patients, considerable amounts of neutral sterols are "lost" during their passage through the intestinal tract. (a) Since plant sterols are largely nonabsorbable in man, they should be totally recovered in the feces; yet in many patients significantly less plant ster...

In a recent study (6), the factors affecting citrate accumulation in tumor slices were ex plored, and the extent of citrate accumulation in tumor slices was found to be dependent upon oxygen tension, pH, and substrate availability. The relationship of citrate formation in tumor slices to the lack of citrate accumulation in fluoroacetate-treated animals is analogous to the differences found in p...

The selective measurement of aldosterone in biological fluids has been handicapped by the lack of specific and sensitive assays. Bioassay methods (l-4) have been limited by the variation inherent in animal response. Chemical methods (5-9) require extensive purification procedures to remove contaminants, and are therefore subject to variable recoveries of the steroid. Furthermore, the quantity o...

Uranium is an alpha-emitting, radioactive, heavy metal that occurs naturally in nearly all rocks and soils. Twenty-two isotopic forms of uranium have been identified, mainly associated with nuclear reactor operations or high-energy physics experiments; the most prevalent isotopes found in the environment are the three naturally-occurring isotopes: U, U, and U. Most uranium isotopes undergo deca...