Radioactive iodine therapy has evolved over the past 70 years from treatment of known metastatic thyroid carcinoma to include adjuvant use to decrease the incidence of recurrent disease and to ablation of normal remnant tissue following thyroidectomy, even for minimal tumor involvement. Advances in laboratory testing, development of drugs useful in radioiodine treatment, as well as advances in ...

Radioiodine uptake is not commonly seen by the thymus gland. On the contrary, the gland is slowly replaced by fat after puberty. Herein, we present 2 patients with papillary thyroid carcinoma, follicular variant, and cervical lymph node involvement. After total/near-total thyroidectomy, the patients received I for ablation therapy. On posttreatment radioiodine scintigraphy, mediastinal I uptake...

Aim: Differentiated thyroid carcinoma has a favorable prognosis, even in the presence of distant metastases, if the tumor cells are able to concentrate radioiodine. Nonetheless, up to 30% of thyroid cancer patients with elevated serum thyroglobulin (Tg) and negative radioiodine whole-body scan findings represent a diagnostic dilemma. In this study we assessed the diagnostic contribution of anat...

INTRODUCTION Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly. CASE PRESENTATION Non-physiological Iodine-131 (I-131) extra...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...

introduction: there is a limited number of case reports published in the past decade confirming the radio-iodine presence in the tear. these observations as well as reported cases of salivary and lacrimal gland dysfunction after radioiodine therapy stimulated investigators to clarify whether lacrimal gland function can be affected post-radioiodine therapy. hence we planned a historical cohort s...

in destroying iodine-concentrating thyroid cells has been harnessed for more than 60 years in the treatment of benign and malignant thyroid diseases. Accumulated experience in large numbers of patients has confirmed the long-term safety and efficacy of radioiodine in the treatment of hyperthyroidism.1,2 Coupled with this is increasing evidence that hyperthyroidism is itself associated with sign...

The incidence of thyroid cancer is low, but when it occurs, it is mainly of the papillary histopathological type. Although PET/CT has a limited role in the diagnosis, it plays a significant role in the overall post-surgery management of a patient with thyroid cancer. This follow-up role is important, especially in patients with elevated serum thyroglobulin, but negative radioiodine whole body s...

The management of patients with differentiated thyroid cancer has changed significantly over the last few decades. Mortality has decreased as the result of earlier detection, refined surgical approaches, subsequent radioiodine ablation, and the development of more sensitive methods for detecting and monitoring disease recurrence. The latter has been facilitated by serum thyroglobulin measuremen...

INTRODUCTION Nuclear power reactors have a large inventory of radioiodine among other radionuclides. In the event of an accident in an operating NPP involving a release of radioactivity, the iodine isotopes will be among the first fission products to be released. Radioiodine isotopes cumulate in the thyroid gland. Therefore protection of the thyroid is one of the most important issues of emerge...