نتایج جستجو برای: radiosynthesis
تعداد نتایج: 363 فیلتر نتایج به سال:
introduction: due to the anti-proliferative properties of platinum group-thiosemicarbazone complexes, the production of 191os-labeled 2-acetyl pyridine 4-n-methylthiosemicarbazone (191os-apmts) was investigated. methods: [191osmium (t½= 15.4d) was produced via the 190os(n,γ)191os nuclear reaction using enriched target irradiated with thermal neutrons. reaction of in-house synthesized 2-acetylpy...
We prepared 11C-labeled 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole ([11C]1) and 4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide ([11C]2) for imaging COX-1 and COX-2 isoforms, respectively, by positron emission tomography. [11C]1 and [11C]2 were synthesized in high radiochemical yields by O-[11C]methylation with [11C]methyl triflate in acet...
Background Fast implementation of positron emission tomography (PET) into clinical and preclinical studies highly demands automated synthesis for the preparation of PET radiopharmaceuticals in a safe and reproducible manner. The aim of this study was to develop automated synthesis methods for these six 18F-labeled radiopharmaceuticals produced on a routine basis at the University of Pennsylvani...
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