We have designed a toolbox that provides an environment for testing radiotherapy optimization techniques, objective functions, and constraints. A set of three-dimensional (3D) pencil beam dose distributions have been computed for a cylindrical phantom. The 6 MV pencil beams were computed using a superposition-based dose engine commissioned for an Elekta SL20 linear accelerator. Due to the cylin...

Introduction: Each treatment planning algorithm has some errors in dose calculation. Particularly these errors are more pronounced in the heterogeneous regions. It is recommended for each set of radiation data and algorithm subtle deliberation done regarding dose calculation accuracy. Knowing the amount of error in dose calculation will result in a fairly accurate estimate of t...

Background: Epidemiological studies have indicated an increasing incidence of radiation induced secondary cancer (SC) in breast cancer patients after radiotherapy (RT), most commonly in the contra-lateral breast (CLB). The present study was conducted to estimate the SC risk in the CLB following 3D conformal radiotherapy techniques (3DCRT) including wedge field and forward intensity modulated ra...

introduction: radiotherapy is a common treatment modality for patients with head and neck malignancies. as the nose lies within the field of radiotherapy of the head and neck, the olfactory fibers and olfactory receptors may be affected by radiation. the aim of this study was to evaluate changes in olfactory threshold in patients with head and neck malignancies who have received radiation to th...

Abstract Background Cancer is one of the leading causes death worldwide. According to GLOBOCAN estimates, there were 341,831 deaths from cervical cancer in 185 countries 2020. The aim this study was compare equieffective dose (EQD 2 ) at Gy per fraction by using volume histograms (DVHs) derived external beam radiotherapy (EBRT) and high-dose rate brachytherapy (HDR-BRT) treatment plans used rad...

In the present work WRF model is used to generate meteorological fields for the HYSPLIT dispersion model. Sensitivity and validation of the WRF model, is conducted by utilizing different combinations of physical parameterization schemes. For this purpose, eight different configurations are examined. Assessment of the predictions of the WRF model is carried out by computing the statistical param...

Convolution/superposition software has been used to produce a library of photon pencil beam dose matrices. This library of pencil beams is designed to serve as a tool for both education and investigation in the field of radiotherapy optimization. The elegance of this pencil beam model stems from its cylindrical symmetry. Because of the symmetry, the dose distribution for a pencil beam from any ...

Although the Monte Carlo (MC) method allows accurate dose calculation for proton radiotherapy, its usage is limited due to long computing time. In order to gain efficiency, a new macro MC (MMC) technique for proton dose calculations has been developed. The basic principle of the MMC transport is a local to global MC approach. The local simulations using GEANT4 consist of mono-energetic proton p...

Introduction: Intraoperative radiotherapy is a radiotherapy technique in which a high single fraction of radiation dose is delivered to the patient after surgery and Concurrent with anesthesia time. The most frequent method for IORT implementation is Intraoperative electron radiotherapy (IOERT), in which, some dedicated and high dose per pulse electron accelerators are employe...