Since the in vitro and in vivo anti-osteoporotic effects of Pueraria mirifica (PM) in rodents have been verified, its activity in menopausal monkeys was evaluated as required before it can be applicable for human use. In this study, postmenopausal osteoporotic monkeys were divided into two groups (five per group), and fed daily with standard diet alone (PMP0 group) or diet mixed with 1000 mg/kg...

BACKGROUND Osteoporosis and associated fractures are a major public health burden and there is great need for a large animal model. Melatonin, the hormone of the pineal gland, has been shown to influence bone metabolism. This study aims to evaluate whether absence of melatonin due to pinealectomy affects the bone mass, structure and remodeling in an ovine animal model. METHODS Female sheep we...

Many fractures occur in individuals without osteoporosis defined by areal bone mineral density (aBMD). Inclusion of other aspects of skeletal strength may be useful in identifying at-risk subjects. We used surrogate measures of bone strength at the radius and tibia measured by peripheral quantitative computed tomography (pQCT) to evaluate their relationships with nonvertebral fracture risk. Fem...

BACKGROUND We report our experience with the use of a full-thickness corticocancellous iliac-crest graft, 1 to 5 centimeters in length - to treat established nonunion of the radius and/or ulna. MATERIAL AND METHODS The technique was used in 14 patients (11 men and 3 women, age 19 to 59). The graft application was combined by rigid fixation with intramedullary locking nail, permitting early ac...

Abstract
 Background: In this study, we examined whether carpal bones (lunate, hamate, capitate) morphologies and fourth metecarp-capitate articulation have an effect on the distal radius fracture pattern.
 
 Methods: 206 patients who applied to emergency department with between 2016-2020 were included in study. Preoperative pre-reduction x-ray films of examined. Lunate, capitate...

Objective - The aim of this study was to measure the ratio of bone cortex (C) to bone diameter (D), (C/D) in radius/tibia, metacarpus /metatarsus and proximal phalanges in fore and hindlimbs to be used as a diagnostic guide in metabolic and nutritional diseases in Minature Donkey. Design- Experimental study Animals- Eight adult Minature donkeys. Procedures- Lateromedial, dorsopalmar and dors...

PURPOSE To evaluate outcomes of wide resection and reconstruction of the distal radius with non-vascularised autogenous fibular grafts for giant cell tumour (GCT) of bone. METHODS Medical records of 7 men and 5 women aged 22 to 47 (mean, 31) years who underwent wide resection of the distal radius and reconstruction with non-vascularised autogenous fibular grafts for GCT of bone were reviewed....

Introduction: Although there are several ways to relief pain in metastatic patients, the use of radionuclides is one of the known and effective ways to relieve the pain caused by bone metastases. The purpose of this study was to assessment of radiation dose distribution of different radioisotopes used to treatment and pain relief patients in a bone-based model based on Monte C...

PURPOSE To examine the influence of ovariectomy (OVX) on bone turnover and trabecular bone mass at the 3 clinically important skeletal sites in mature cynomolgus monkeys. MATERIALS AND METHODS Six female cynomolgus monkeys, aged 17-21 years, were randomized into 2 groups by the stratified weight: the OVX and sham-operation groups (n = 3 in each group). The experimental period was 16 months. L...