The causes of central nervous system (CNS) dysfunction in uremia are not well known and are not completely reversed by dialysis. This problem was investigated in synaptosomes, which are membrane vesicles from synaptic junctions in the brain. We measured Na uptake under conditions of control, veratridine stimulation, and tetrodotoxin inhibition, in synaptosomes from normal and acutely uremic (bl...

Salt stress is one of the most chalanging abiotic stresses affecting natural productivity and causing significant croplosses worldwide. A greenhouse experiment was conducted to evaluate the response of two alfalfa cultivars (Bamiand Hamedani) to 6 levels of salinity (0 as control, 25, 50, 75, 100, 125 mM NaCl) at the College of Agriculture,Shiraz University, Shiraz, Iran in 2008. Plant dry weig...

Salinity is an environmental stress that limits growth and development in plants. Due to high salinity in Khuzestan soils it is necessary to identify cultivars with appropriate yield that are compatible with Khuzestan conditions. This experiment was done to evaluate three rice cultivars for salinity tolerance at seedling stage by measuring the absorption of sodium and potassium ions and the rat...

Vegetative plants of certain seaweeds were collected from the natural habitat of Kilakarai and Mandapam coast were subjected to SEM-energy dispersive spectroscopic analysis and quantified the following minerals viz., Na, Mg, Si, S, Cl, K, Ca, Mn, P, Fe, Zn and Cr during summer, pre-monsoon, monsoon and post-monsoon seasons in 2007-2008. The order of preferential accumulation of elemental compos...

PURPOSE Increased lenticular oxidative stress and altered calcium/magnesium (Ca/Mg) homeostasis underlie cataractogenesis. We developed a liposomal formulation of magnesium taurate (MgT) and studied its effects on Ca/Mg homeostasis and lenticular oxidative and nitrosative stress in galactose-fed rats. METHODS The galactose-fed rats were topically treated with liposomal MgT (LMgT), liposomal t...

Arbuscular mycorrhizal (AM) symbiosis can enhance plant resistance to NaCl stress in several ways. Two fundamental roles involve osmotic and ionic adjustment. By stimulating accumulation of solutes, the symbiosis can help plants sustain optimal water balance and diminish Na(+) toxicity. The size of the AM effect on osmolytes has varied widely and is unpredictable. We conducted a meta-analysis t...

OBJECTIVE To determine the effect of the most commonly abused drugs (tramadol and morphine), on acetylcholine esterase (AChE), Na+/K+-ATPase activities and related parameters, Na+ and K+ as biomarkers of neurotoxicity. METHODS Tramadol - as a weak μ opioid receptor agonist- and morphine - as opiate analgesic drugs, were chosen for the present study. Four series of experimental animals were co...

Apart from Na(+),K(+)-ATPase, a second sodium pump, Na(+)-stimulated, K(+)-independent ATPase (Na(+)-ATPase) is expressed in proximal convoluted tubule of the mammalian kidney. The aim of this study was to develop a method of Na(+)-ATPase assay based on the method previously used by us to measure Na(+),K(+)-ATPase activity. The ATPase activity was assayed as the amount of inorganic phosphate li...

A protein of approximately 70-kDa was identified as a candidate Na+/Mg2+ exchanger in rumen epithelial cells (REC). Melastatin-related Transient Receptor Potential 7 (TRPM7) and Magnesium Transporter 1 (MagT1) transcripts and, from them, encoded proteins were also detected. The regulation of these Mg transport pathways by extracellular [Mg] changes was the main focus of this study. Therefore, a...

Erythrocyte magnesium (Mg2+) deficiency has been demonstrated in sickle cell disease to contribute to erythrocyte dehydration, K loss, and thus sickling. No studies have assessed the functional properties of the Na/Mg exchanger in sickle cell disease. Using Mg(2+)-loaded erythrocytes, we measured Mg2+ efflux induced by extracellular Na+. We estimated that the Na/Mg exchanger had higher maximal ...