Infections of pigs with Salmonella enterica subspecies enterica serovar Typhimurium (Salmonella Typhimurium) often result in the development of carriers that intermittently excrete Salmonella in very low numbers. During periods of stress, recrudescence of Salmonella may occur. The mechanism of stress related re-excretion of Salmonella by pigs is poorly understood and the aim of the presented st...

Previously, we reported JPC-2997 [4-(tert-Butyl)-2-((tertbutylamino)methyl)-6-(6-(trifluoromethyl)pyridin-3-yl)phenol] to possess high in vitro antimalarial activity against Plasmodium falciparum lines, low cytotoxicity in mammalian cell lines, a long blood elimination half-life in Aotus monkeys (10.8 days), and potent in vivo efficacy against animal malaria models (1). Herein, as planned by Bi...

We report the results of low friction arthroplasty in 72 old tuberculous hips and 42 hips with old quiescent septic arthritis. Follow-up was for a minimum of two years. Recrudescence of tuberculosis was seen in only one patient, but deep infection occurred in four of the hips with previous septic arthritis. The reasons for this are discussed. It is recommended that patients with old tuberculous...

We investigated the relationship between the two main molecular markers for chloroquine resistance (Pfcrt T76 and Pfmdr-1 Y86) and the clinical efficacy of amodiaquine in Burkina Faso. Before treatment, the prevalence of Pfcrt T76, Pfmdr-1 Y86 or both mutations in the same infection was significantly higher in patients who experienced a recrudescence than in those who successfully responded to ...

After the remission of symptoms and reduction in spleen size while on proguanil therapy four patients with the tropical splenomegaly syndrome defaulted from treatment. The withdrawal of proguanil caused a recrudescence of original symptoms, splenomegaly, and a return of the initially raised serum IgM. Complete return to normal values was again effected with proguanil therapy.The role of the spl...

A well proven treatment protocol, which has been published in similar form many times, is used. Initially, the dosage is gradually increased on a weekly basis, then constant dose rates are injected subcutaneously. After reaching the maintenance dose the injections are applied in 2-4 week intervals. In veterinary medicine, the ASIT is recommended as at least 1 year lasting or even lifelong thera...

Recently a number of studies have reported worldwide recrudescence of biochemical and clinical rickets, despite continuous revisions of the experts about the adequate intake of vitamin D for infants and children to maintain an adequate 25-hydroxyvitamin D status and assure the achievement of peak bone mass during the growth. The aim of this review is to illustrate the current opinions and contr...