diadema setosum (leske, 1778), is one of the common echinoids widely distributed in the indo-west pacific ocean, where it occurs from the red sea, persian gulf and the east coast of africa to japan, australia and malaysia. to investigate the developmental basis of morphological changes in embryos and larvae, we documented the ontogeny of d. setosum in a controlled laboratory condition at the in...

The properties of Na+-dependent L-alanine transport in human erythrocytes were investigated using K+ as the Na+ substitute. Initial rates of Na+-dependent L-alanine uptake (0.2mM extracellular amino acid) for erythrocytes from 22 donors ranged from 40 to 180pmol/litre of cells per h at 370C. Amino acid uptake over the concentration range 0.1-8mm was consistent with a single saturable component ...

Erythroid ferritin was isolated from tadpole red blood cells, an unusually abundant source, with an iron content of 12%. The apoprotein was characterized by sedimentation equilibrium studies, sodium dodecyl sulfate gel electrophoresis, and by determination of amino acid composition. Tadpole red cell apoferritin has a molecular weight of 478,000, a subunit size of 19,600, and an amino acid compo...

By RICHARD I. WALKER, J. C. HERIOX AND S. \V. SMITH, Jn. A N UNEXPECTED INCREASE in resistance to osmotic lysis of red cells passed through cotton has been observed many times in this laboratory during procedures for obtaining samples of pure lymphocytes for chemical analysis1 and in vitro culture.2 This increased resistance has been manifest by incomplete lysis on exposure to hypotonic solutio...

Purine nucleosides have been reported to extend the preservation of red cells stored in acid citrate dextrose (ACD) (1-6). This effect was originally attributed to the production of phosphorylated ribose as an energy substrate within the erythrocyte (7-9) through the action of nucleoside phosphorylase (10). This enzyme was shown to act on inosine, guanosine (11, 12), and on adenosine after its ...

Hematopathology is not only the study of disease of the blood and bone marrow, but also of the organs and tissues which employ blood cells as principal effectors of their physiologic functions. Such would include the lymph nodes, spleen, thymus, and the many foci of lymphoid tissue found along the aerodigestive tract. Generally two types of medical subspecialists intensively practice in this ar...

132-m (2) and tryptophan in Rab 12 kD (1). The possibility that the assignment of tryptophan results from a typographical error in figure 2 of Brinckerhoff et al. (1) is suggested by the misquoted assignment in that figure of tryptophan, instead of tyrosine, at the same position of human P2-m, the only sequence to which Rab 12 kD is compared. PETER PARHAM Department of Cell Biology, Shernan Fai...

New automated blood cell analyzers provide an index of red cell volume distribution width (RDW) or heterogeneity and a histogram display of red cell volume distribution. We have developed a classification of red cell disorders, based on mean corpuscular volume (MCV) or red cell size, heterogeneity, and histograms, to guide diagnosis from the peripheral blood analysis. The distinction of iron de...

In a group of normal subjects going from sea level to approximately 16,000 feet we observed that very soon after arrival at high altitude there was hemoconcentration, as indicated by an increased red cell count and hematocrit, but a normal total red cell volume and a low plasma volume. This "apparent increase" in the number of red blood cells in the early days after arrival at high altitude is,...