Significant progress has been made in preventing acute allograft rejection following solid organ transplantation resulting in improved allograft survival. However, long term function still remains disappointing primarily due to chronic allograft rejection. Alloimmune responses primarily defined by the development of antibodies (Abs) to donor mismatched major histocompatibility antigens during t...

While it has been documented that perceived parental rejection is associated with the use of alcohol, it has not been documented if perceived parental rejection is associated with drinking motives, or self-perceived reasons for drinking alcohol. Therefore, the purpose of the present study was to determine if, among young women specifically, perceived parental rejection has an indirect effect, v...

HUMORAL rejection is a rare but potentially fatal form of acute allograft rejection. Pathophysiologically, allosensitization against graft determinants occurs either preor posttransplantation. Preformed antibodies lead to the phenomenon of hyperacute rejection. The de novo synthesized antibodies directed against HLA antigens expressed on graft endothelium are clearly associated with humoral rej...

Advances in microsurgical techniques and immunomodulatory protocols have contributed to the expansion of vascularized composite allotransplantation (VCA) with very encouraging immunological, functional, and cosmetic results. Rejection remains however a major hurdle that portends serious threats to recipients. Rejection features in VCA have been described in a number of studies, and an internati...

Classic hyperacute rejection is dependent on the activation of the terminal components of complement. Recently, xenoantibodies with limited abilities to activate the classical pathway of complement in vitro have been implicated in the acute vascular rejection of xenografts. It is unclear how these Abs affect their pathogenic activities in vivo. In this study, we demonstrate the ability of an an...

background: despite advances in the medical care of renal transplant recipients which have led to an improvement in allograft survival, renal allograft rejection is still a major ob-stacle to successful organ transplantation. understanding the mechanisms contributing to allograft rejection will be of great importance for the development of efficient antirejection strategies. objective: the aim ...

nanofiltration (nf) has become a widely accepted process not only for producing drinking water but also for recovering wastewater in industrial processes or removing pollutants from industrial wastewater effluent. in the textile industry, the treatment of various dye baths with nf at room temperature have already been studied and was found feasible at lab-scale and pilot scale. the aim of this ...

the main objevtive  of  the study is to determine the factors which influence the addeptance or rejection of rural livestock insurance in garmsar. the research method is descriptive one. there are  two groups of  research populations: 1467 cases in acceptance group & 7000 cases in rejection group. the sample population is 320 cases among 8467 ones. data collection instrumennt is questionnaire. ...

ackground: Gene expression profiling distinguishes the absence or presence of moderate to severe grades of acute cellular rejection in cardiac allograft recipients using a 20-gene classifier. We explored the hypothesis that the rejection classifier also differentiates various forms of mild rejection and we performed sub-analyses based on time post-transplant and confirmatory pathology interpret...

BACKGROUND Assessment of gene expression in peripheral blood may provide a noninvasive screening test for allograft rejection. We hypothesized that changes in peripheral blood expression profiles would correlate with biopsy-proven rejection and would resolve after treatment of rejection episodes. METHODS AND RESULTS We performed a case-control study nested within a cohort of 189 cardiac trans...