kidney transplantation is the most common transplantation in the world. annually, a large number of patients that have chronic renal failure are undergoing renal transplantation and the major subject about these patients is the rejection of graft that should be controlled by immunosuppressive agents.  the aim of this study is investigation of the effect of cyclosporin against tacrolimus in pati...

INTRODUCTION Rituximab (RTX) therapy of rheumatoid arthritis (RA) exhibits enhanced effectiveness in seropositive patients. Using patient sera, we tested if this improved efficacy was associated with enhanced RTX mediated complement-dependent cytotoxicity (RTX-CDC). METHODS We developed an in vitro assay for RTX-CDC using patient sera and the Daudi human B cell line. Using propidium iodide up...

Background:  Renal transplantation is the best choose in the end stage renal disease (ESRD), and acute rejection and graft dysfunction remain major challenges in the worldwide, even with the advent of new immunosuppressive drugs. The novel cell-based anti-rejection treatments have been studied by using different stem cell sources. In this study, transplantation of autologous-bone-marrow-derive...

Recently, with use of rat dorsal root ganglion (DRG) neurons we have been able to dissociate the binding affinities of vanilloids from their potencies to induce 45Ca uptake, which suggests the existence of distinct classes of the vanilloid receptor (). In the present study, we have demonstrated that the ultrapotent capsaicin analog resiniferatoxin (RTX) desensitized rat DRG neurons to the subse...

*Corresponding author: Dr. Andreas Kronbichler, Medical University Innsbruck, Department of Internal Medicine IV, Nephrology and Hypertension, Anichstraße 35, 6020 Innsbruck, Austria. E-mail: [email protected] Randomized controlled trials have revolutionised the treatment options in small vessel vasculitis. From large genome wide association studies we have learned that granulomat...

BACKGROUND AND OBJECTIVES The reliability and usefulness of the right ventricular (RV) Tei index (RTX) remains controversial because it has not been possible to simultaneously measure RV inflow and outflow. However, dual pulsed-wave Doppler (DPD) enables flow velocities to be obtained at different sampling sites simultaneously. In this study we evaluated the feasibility and reliability of RTX v...

Causes of death in pediatric systemic lupus erythematosus Sirs, Pediatric systemic lupus erythematosus (pSLE) remains a severe disease although its prognosis has improved with time. Use of new therapies may result in modifying the causes of mortality. Death was mostly due to renal insufficiency and infections (1-4) during the 1980-1990 decade, while no death was recorded in the sole study enrol...

background: infective endocarditis (ie) is a serious complication in immunosuppressive patients that has adverse effects. objectives: the aim of this study was to define the characteristics, outcomes, and correlating factors of mortality in renal transplant recipients. patients and methods: infective endocarditis was diagnosed in 22 patients from three renal transplant centers in iran between 2...

results the accuracy for detecting number of main renal arteries were not different in both groups which were 96.7% in ct angiography group and 90% in traditional angiography group (p = 0.15). the accuracy for detection of main renal veins were 100% in group 1 and 96.7% in group 2 (p = 0.31). patients and methods a total number of 60 living kidney donors who underwent open surgical approach for...