We report a 27-year-old woman who developed Coombs' negative hemolytic anemia and fulminant hepatic failure as the initial manifestation of Wilson's disease. Unmeasurably low level of serum alkaline phosphatase provided a clue to the diagnosis of Wilson's disease. The diagnosis was established with the presence of Kayser-Fleischer ring, decreased serum ceruloplasmin level, and elevated urine an...

Heart failure is a deadly disease that has reached epidemic proportions in industrialized countries. Patients living with heart failure carry a heavy burden in terms of morbidity. Many patients require repeated hospitalizations for cardiovascular problems, especially for episodes of worsening heart failure. In fact, heart failure is one of the most important causes of hospital admissions in the...

AA amyloidosis is a classic and serious complication of many chronic inflammatory processes, whether infectious, autoimmune, or neoplastic origin. It frequently complicated by kidney damage, often in the form nephrotic syndrome. Giant cell arteritis common elderly; however, it rarely causes amyloidosis. We report rare case Horton disease causing an elderly patient with history myopericarditis r...

BACKGROUND Portal vein embolization (PVE) is used routinely to prevent postoperative liver failure as a result of anticipated insufficient future liver remnant volume following resection. The authors have recently developed a technique for temporary PVE. The aim of this study was to assess the effect of repeated reversible PVE on hepatocyte proliferation and subsequent liver hypertrophy in rode...

Botulinum neurotoxin injections are a valuable treatment modality for many therapeutic indications as well as in the aesthetic field for facial rejuvenation. As successful treatment requires repeated injections over a long period of time, secondary resistance to botulinum toxin preparations after repeated injections is an ongoing concern. We report five case studies in which neutralizing antibo...

We consider the problem of Generic Repeated Coordination, of which Reliable Broadcast and Repeated Distributed Consensus are but two instances. We show that in the absence of in nite storage capacity, all problems in this class require perfect failure detectors, highlighting signi cant assumptions made by many protocols assuming reliable broadcast. Our work also shows that the usual reason used...

Abstract This paper studies a simple model of repeated cartel that can punish using both voluntary fines and inefficient prices wars. The idea is to use the in response noisy signals bad behavior back it up with threats price wars easily observed failure pay fines. shown deliver insights modern game theory an empirically accurate tractable form.

Most patients diagnosed with secondary hemochromatosis have had repeated blood transfusions. Cardiac failure accounts for approximately one-third of the deaths associated with hemochromatosis. Liver dysfunction or hormonal disorders such as diabetes generally precede cardiac failure. A 23-year-old woman with hemochromatosis had, despite significant left ventricular dysfunction, liver function w...

Sepsis is associated with failure of multiple organs, including failure of the immune system. The resulting 'sepsis-associated immunosuppression' resembles a state of immunological anergy that is characterized by repeated 'infectious hits', prolonged multiple-organ failure, and death. As a consequence, adjunctive treatment approaches using measures of immunostimulation with colony-stimulating f...