Alexander disease, less commoniy known as fibrinoid leukodystrophy is an extremely rare, non- familial, progressive, lethal leukodystrophy which is characterized predominantly by abnormalities of white matter in bilateral frontal regions. It usually presents early within first 2 years of life with clinical features of macrocephaly, recurrent seizures and psychomotor retardation. Diagnosis of th...

background: epilepsy is a chief communal health problem. antiepileptic drugs only provide symptomatic treatment. walnut kernels (wk) have high concentrations of phenolic compounds, which have beneficial effects on human health because of their antioxidant and anti-atherogenic properties. the present study was designed to evaluate the efficacy of wk supplementation for the prevention of experime...

how to cite this article: salehiomran mr, mahzari m. zinc status in febrile seizure: a case-control study. iran j child neurol. 2013 autumn; 7(4):20-23. objective febrile seizure is the most common type of seizure in children. their incidence is 2-5%. there are different hypotheses about relationship between neurotransmitters and trace elements (such as zinc) and febrile seizure. zinc, as a maj...

introduction a sudden loss of consciousness followed by abnormal movements can be ictal or syncopal in origin. transient response by the brain to sudden decrease of blood flow may cause sudden loss of consciousness followed by abnormal movements that mimic seizure. dysrhythmia is one of the important and critical reasons of such events that should be differentiated from seizure. case presentati...

how to cite this article: poudel p, chitlangia m, pokharel r. predictors of poor seizure control in children managed at a tertiary care hospital of eastern nepal iran j child neurol. summer 2016; 10(3):48-56.   abstract objective various factors have been claimed to predict outcome of afebrile seizures in children. this study was aimed to find out the predictors of poor seizure control in child...

how to cite this article: mahyar a, ayazi p, dalirani r, bakhtiyari h, daneshi khohan mm, javadi a. a case-control study of the association between serumcopper level and febrile seizures in children. iranian journal of child neurology 2012;6(1):23-28. objective febrile seizures are the most common cause of seizure in children. identification of risk factors is very important. this study was con...

introduction: temporal lobe epilepsy (tle) is the most common and drug resistant epilepsy in adults. due to behavioral, morphologic and electrographic similarities, pilocarpine model of epilepsy best resembles tle. this study was aimed at determination of the changes in electroencephalogram (eeg) sub-bands amplitude during focal seizures in the pilocarpine model of epilepsy. analysis of these c...

Ghrelin, des-acyl ghrelin and other related peptides possess anticonvulsant activities. Although ghrelin and cognate peptides were shown to physiologically regulate only the ghrelin receptor, some of them were pharmacologically proved to activate the peroxisome proliferator-activated receptor gamma (PPARγ) through stimulation of the scavenger receptor CD36 in macrophages. In our study, we chall...

A woman with temporal lobe epilepsy manifesting with repeated episodes of sudden diarrhea and loss of consciousness is reported. A 63-year-old, right-handed female presented with chief complaints of sudden diarrhea and loss of consciousness for almost three decades. The first attack occurred in her 30s, and similar attacks repeated several times in a year. Her attacks comprised abrupt abdominal...