introduction: medication errors are among the most serious health errors threatening patient safety in all countries, with major impacts on public health. midwives as members of healthcare systems are prone to such errors. therefore, in this study, we aimed to determine medication errors and the contributing factors among midwives working in maternity units of mashhad university of medical scie...

Evaluating whether a new medication prolongs QT intervals is a critical safety activity that is conducted in a sensitive animal model during non-clinical drug development. The importance of QT liability detection has been reinforced by non-clinical [International Conference on Harmonization (ICH) S7B] and clinical (ICH E14) regulatory guidance from the International Conference on Harmonization....

Current testing for proarrhythmic potential of drugs relies on determining their effect on the QT interval of the ECG. Because QT prolongation is frequently associated with blockade of the human ether-à-go-go related gene (hERG) channel, the International Conference on Harmonization (ICH) S7B guideline recommends an hERG inhibition assay as the first proxy for identifying such potential risk. S...

One of the most enduring points of confl ict in the global political economy is whether international economic rules and regulations should accommodate diversity or encourage harmonization of regulatory institutions. The logic of diff erentiation is that optimal regulatory design diff ers according to national needs and conditions. The logic of harmonization, in contrast, is that the transactio...

detection of adverse drug reactions (adrs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. spontaneous reporting of adrs is scare and several obstacles to such reporting have been identified formerly. this study aimed to determine the role of clinical pharmacy residents in adr reporting within a hospital setting.clinical pharmacy resi...

background: fatalism, an obstacle to the adoption of safe behaviors, describes the belief that injuries are unavoidable and occur due to haphazard or fate. the present study examined degree of fatalism related to injuries reporting rate and its dimensions among workers’ isfahan steel company. methods: a self-administered anonymous was distributed to 250 workers. the survey included demographic ...

Introduction. The list of priority European integration measures in Ukraine envisages further harmonization the national financial monitoring system with FATF international standards (recommendations). Therefore, it is important to analyze both results assessment technical compliance anti-legalization sphere recommendations, and their effectiveness. Problem Statement. Assessment degree preventi...