The expression of a P-glycoprotein (Pgp1) cDNA encoding two amino acid substitutions in the sixth transmembrane domain of the protein (G338A339 to A338P339) confers a unique cross-resistance profile that displays preferential resistance to actinomycin D and diminished resistance to colchicine and daunorubicin. We report here that this multidrug-resistant phenotype is also insensitive to reversa...

The purpose of this study was to analyse the profile of antimicrobial resistance among 21 strains of Salmonella isolated from patients with gastroenteritis symptom. It was observed that S. enteritidis was the serotype prevalent. These strains were sensitive to the majority of the antimicrobials tested, however, high resistance was observed in S. typhimurium and S. enterica subsp. enterica serot...

OBJECTIVE To evaluate insulin resistance and lipid profile in women with congenital adrenal hyperplasia (CAH) caused by classical 21-hydroxylase deficiency (21OHD), and their association with body mass index (BMI) and corticosteroid dosage. SUBJECTS AND METHODS We assessed BMI, waist circumference, current glucocorticoid dosage, glucose, insulin and lipid profile in eighteen young women (mean...

shigellosis is an acute gastroenteritis caused by shigella species. the purpose of this study was to determine plasmid profile, antibiotic resistance and phenotypic virulent by congo red between s. flexneri strains. the isolated bacteria were identified by standard bacterial and biochemical methods. plasmids were isolated by alkaline lysis method. antibiotic susceptibility test was performed ac...

Background: Blood stream infection is one of the main causes of morbidity and mortality in patients with cancer. The purpose of this study was to evaluate the prevalence of aerobic and anaerobic-bacteremia in hospital inpatients with cancer and to determine the antibiotic resistance profile in isolated organisms in Kerman, southeast Iran. Methods: Total of 240 blood cultures from 136 patients w...

retinol binding protein4 (rbp4) such as adipocytokines that could be a marker for type 2 diabetes and seems to be leading to increased insulin resistance. the purpose of this study was to evaluate the effect of aerobic training on serum rbp4 and insulin resistance in adult male rats. in the present experimental study 16 wistar rats were randomly divided to one of the exercise group (n=10) or co...

the incidence of virulence factors among 114 enterococcus faecalis and 35 enterococcus faecium strains from different clinical specimens were compared with those isolated from control groups. a few of the isolates expressed two or more of the following traits simultaneously: hemolysin, aggregation substance, gelatinase, dnase, hemagglutinin and antibiotic resistance. the frequencies of hemolysi...