BACKGROUND Compromised iron status is important in restless legs syndrome pathophysiology. We compared the efficacy and tolerability of ferric carboxymaltose (single intravenous dose) versus placebo for restless legs syndrome treatment in iron-deficient nonanemic patients. METHODS Patients with moderate to severe restless legs syndrome and serum ferritin < 75 μg/L (or serum ferritin 75-300 μg...

Asymmetric leg function is often an undesired side-effect in artificial legged systems and may reflect functional deficits or variations in the mechanical construction. It can also be found in legged locomotion in humans and animals such as after an accident or in specific gait patterns. So far, it is not clear to what extent differences in the leg function of contralateral limbs can be tolerat...

Restless legs syndrome (RLS) is one of the commonest movement disorders affecting sleep and also daytime functioning. The prevalence may be 8%-10% of the white Caucasian population. The diagnosis is simple and is based on a well-validated clinical questionnaire, yet misdiagnosis is common and the condition remains underdiagnosed and consequently inappropriately treated, often causing great dist...

Data collected from medical literature indicate that dopaminergic agonists alleviate Restless Legs Syndrome symptoms while dopaminergic agonists antagonists aggravate them. Dopaminergic agonists is a physiological regulator of thyroid-stimulating hormone. Dopaminergic agonists infusion diminishes the levels of thyroid hormones, which have the ability to provoke restlessness, hyperkinetic states...

OBJECTIVE Training models are required to impart surgical skills, like wound closure techniques, prior to practice in patients. In an ideal case, the tissue characteristics of the model are close to those of humans, easy to create and of low cost. METHODS Here, we describe a model to train students in wound closure technique using conventional chicken legs obtained from the supermarket. RES...

Newportia (Newportia) spelaea n. sp. and Newportia (N.) potiguar n. sp. are here described from Bahia and Rio Grande do Norte State, respectively. These two species show highly troglomorphic traits, such as elongation of antennae, legs, ultimate legs, tergites, pronounced depigmentation and reduced sclerotization of the cuticle. Both species occur in caves located in a semi-arid biome (Caatinga...

According to the POST, herpetologists (scientists who study amphibians and reptiles) have reported finding frogs with missing legs, extra legs, misshapen legs, paralyzed legs that stuck out from the body at odd places, legs that were webbed together with extra skin, legs that were fused to the body, and legs that split into two half-way down. They have also found frogs with missing eyes. One on...