نتایج جستجو برای: rhenium 186
تعداد نتایج: 10553 فیلتر نتایج به سال:
Prostate cancer is one of the leading causes of cancer deaths among men, many miRNAs have been demonstrated to play critical role in the progression of prostate cancer, miR-186 suppresses the progression of many tumors, such as bladder cancer and glioma. Previous study shows miR-186 is downregulated in prostate cancer tissues, and is a good prognosis for prostate cancer patients. In this study,...
UNLABELLED We proposed a new water-soluble rhenium diseleno-ether compound (with one atom of Re and two atoms of Se) and investigated the uptake of Re into the nucleus of malignant cells in culture exposed to the compound for 48 h and its efflux from the nucleus after a post-exposure period of 48 h, as DNA is the main target of Re. We also studied the distribution of both Re and Se in the main ...
Relapsed/refractory multiple myeloma represents a major challenge in multiple myeloma therapy. For patients with relapsed/refractory multiple myeloma, we developed a treatment schema of metronomically scheduled drug therapy. We identified 186 patients who had been treated with metronomic therapy between March 2004 and January 2012 with a median follow up of 24.2 months. Median age was 61 years ...
Background: To investigate the role of miR-186 in the carcinogenesis and metastasis of human urothelial bladder cancer and its potential target protein. Methods: Quantitative real-time PCR (qRT-PCR) was performed to detect miR-186 expression in human urothelial bladder cancer tissues and cell lines. Then, Bioinformatics analysis, combined with luciferase reporter assay demonstrated the miR-186’...
BACKGROUND Increasing evidence has shown that microRNAs function as oncogenes or tumor suppressors in human malignancies, but the roles of miR-186 in human bladder cancer (BC) is still unclear. METHODS First, quantitative real-time PCR (qRT-PCR) was performed to detect miR-186 expression in bladder cancer tissues and cell lines. Then, Bioinformatics analysis, combined with luciferase reporter...
In situ prepared lithium arylselenolates {LiSePh, LiSe(2,6-Me2Ph), LiSe(2,4,6-Me3Ph)} or -tellurolates {LiTePh, LiTe(2,6-Me2Ph), LiTe(2,4,6-Me3Ph)} react with [ReOCl3(PPh3)2] and (NBu4)Br in good yields under formation of rhenium(V) complexes the composition (NBu4)[ReO(L)4)]. The first oxidorhenium(V) complex four monodentate phenolato ligands, [ReO(2,6-Me2Ph)4]?, was isolated crystalline form....
Abstract Childhood ependymoma and HGG are difficult tumors to treat. Recurrent is treated with re-resection multiple rounds of external beam radiation therapy (EBRT). chemoradiation followed by clinical trials, if available. While EBRT remains a central component management, it limited tolerance the surrounding normal brain tissue. Rhenium-186 NanoLiposome (186RNL) permits selective delivery be...
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