in this paper, we introduce new classes $sum_{k,p,n}(alpha ,m,lambda ,l,rho )$ and $mathcal{t}_{k,p,n}(alpha ,m,lambda ,l,rho )$ of p-valent meromorphic functions defined by using the extended multiplier transformation operator. we use a strong convolution technique and derive inclusion results. a radius problem and some other interesting properties of these classes are discussed.

The statistical description of the scalar conservation law form $\rho_t=H(\rho)_x$ with $H: \mathbb{R} \rightarrow \mathbb{R}$ a smooth convex function has been an object interest when initial profile $\rho(\cdot,0)$ is random. special case $H(\rho)=\frac{\rho^2}{2}$ (Burgers equation) in particular received extensive past and now understood for various random conditions. We solve this paper co...

In prokaryotes, genes belonging to the same operon are transcribed in a single mRNA molecule. Transcription starts as the RNA polymerase binds to the promoter and continues until it reaches a transcriptional terminator. Some terminators rely on the presence of the Rho protein, whereas others function independently of Rho. Such Rho-independent terminators consist of an inverted repeat followed b...

The Rho signaling pathway regulates the cytoskeleton and motility and plays an important role in neuronal growth inhibition. Here we demonstrate that inactivation of Rho or its downstream target Rho-associated kinase (ROK) stimulated neurite growth in primary cells of cortical neurons plated on myelin or chondroitin sulfate proteoglycan substrates. Furthermore, treatment either with C3 transfer...

Cardiovascular diseases are associated with chronic activation of Rho-associated kinase. Rho-associated kinase activity is significantly correlated with endothelial function and Framingham risk score. However, there is no information on the prognostic value of Rho-associated kinase activity. We evaluated Rho-associated kinase activity in peripheral leukocytes by Western blot analysis in 633 sub...

Thrombin induces astrocytoma cell rounding through a Rho-dependent pathway (Majumdar, M., Seasholtz, T. M., Goldstein, D., de Lanerolle, P., and Brown, J. H. (1998) J. Biol. Chem. 273, 10099-10106). The involvement of the G(12) family of G proteins and the role of specific Rho exchange factors in transducing signals from the thrombin receptor to Rho-dependent cytoskeletal responses was examined...

During Gram-negative sepsis bacterial LPS induces endothelial cell contraction, actin reorganization, and loss of endothelial integrity by an unknown signal mechanism. In this study, we provide evidence that LPS-stimulation of endothelial cells (HUVEC) decreases myosin light chain (MLC) phosphatase, resulting in an increase in MLC phosphorylation followed by cell contraction. All of these LPS e...

The classical monomer-dimer model in two-dimensional lattices has been shown to belong to the "#P-complete" class, which indicates the problem is computationally "intractable." We use exact computational method to investigate the number of ways to arrange dimers on mxn two-dimensional rectangular lattice strips with fixed dimer density rho . For any dimer density 0<rho<1 , we find a logarithmic...

BACKGROUND The Rho GTPases A, B and C proteins, members of the Rho family whose activity is regulated by GDP/GTP cycling, function in many cellular pathways controlling proliferation and have recently been implicated in tumorigenesis. Although overexpression of Rho GTPases has been correlated with tumorigenesis, only their GTP-bound forms are able to activate the signalling pathways implicated ...