Zhang C, Adamos C, Oh MJ, Baruah J, Ayee MA, Mehta D, Wary KK, Levitan I. oxLDL induces endothelial cell proliferation via Rho/ROCK/Akt/p27 signaling: opposite effects of oxLDL and cholesterol loading. Am J Physiol Cell Physiol 313: C340 –C351, 2017. First published July 12, 2017; doi:10.1152/ ajpcell.00249.2016.—Oxidized modifications of LDL (oxLDL) play a key role in the development of endoth...

Heterotrimeric G proteins, G12 and G13, have been shown to transduce signals from G protein-coupled receptors to activate Rho GTPase in cells. Recently, we identified p115RhoGEF, one of the guanine nucleotide exchange factors (GEFs) for Rho, as a direct link between Galpha13 and Rho [Kozasa, T., et al. (1998) Science 280, 2109-2111; Hart, M. J., et al. (1998) Science 280, 2112-2114]. Activated ...

Muniyappa, Ranganath, Rui Xu, Jeffrey L. Ram, and James R. Sowers. Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 278: H1762–H1768, 2000.— Inducible nitric oxide synthase (iNOS) in vascular smooth muscle cells (VSMCs) is upregulated in arterial injury and plays a role in regulating VSMC proliferation and restenosis. Infl...

A quantum mechanical model is developed for the observed resonance enhancement of light scattering by aggregates of electronically interacting chromophores. Aggregate size, monomer oscillator strength, extent of electronic coupling, and aggregate geometry are all important determinants of intensity in resonance light scattering (RLS) spectra. The theory also predicts the value of the depolariza...

Submitted to: Journal of Bacteriology 1 Section: Genetics and Molecular Biology 2 3 4 Modulation of Rho-dependent transcription termination in Escherichia coli by the H-NS 5 family of proteins 6 7 8 Running title : H-NS and Rho-dependent termination 9 10 11 Shivalika Saxena and J. Gowrishankar * 12 13 Laboratory of Bacterial Genetics, Centre for DNA Fingerprinting and Diagnostics, 14 Hyderabad ...

Altered Patterns of Protein Synthesis in Infection by SV40 Mutants P. Tegtmeyer The Semiautonomous Replicon: A Molecular Model for the Oncogenicity of SV40 R. G. Martin, J. Y. Chou, J. Avila and R. Saral Transformation of Primate and Rodent Cells by Temperature-sensitive Mutants of SV40 J. S. Butel, J. S. Brugge and C. A. Noonan Properties of Temperature-sensitive Mutants of Polyoma Virus W. Ec...

Rhodopsin (Rho) resides within internal membrane structures called disc membranes that are found in the rod outer segments (ROS) of photoreceptors in the retina. Rho expression is essential for formation of ROS, which are absent in knockout Rho-/- mice. ROS of mice heterozygous for the Rho gene deletion (Rho+/-) may have a lower Rho density than wild type (WT) membranes, or the ROS structure ma...

In this work, we perform a systematic study of the mass spectra, root mean square(r.m.s.) radii and radial density distributions doubly charmed baryons $\Xi_{cc}$ $\Omega_{cc}$. The calculations are carried out in frame work Godfrey-Isgur (GI) relativized quark model, where baryon is regarded as real three-body system quarks. Our results show that excited energy with $\rho$-mode lower than thos...

Fully dehydrated and partially sodium-cesium containing RHO zeolite (Na,Cs-RHO) shows a genuine inflection in the CO2 isotherms in the temperature range 293-333 K that can be attributed to a sorbate-induced framework deformation from an acentric (A) to a centric (C) phase due to a partial cation rearrangement. This peculiar sorption pattern can be captured by the formulation of thermodynamic is...