نتایج جستجو برای: rhodanine assay

تعداد نتایج: 221895  

2016
Paul B Geraghty Calvin Lee Jegadesan Subbiah Wallace W H Wong James L Banal Mohammed A Jameel Trevor A Smith David J Jones

The synthesis of key 4-alkyl-substituted 5-(trimethylsilyl)thiophene-2-boronic acid pinacol esters 3 allowed a simplified alkylthiophene catenation process to access bis-, ter-, quater-, and quinquethiophene π-bridges for the synthesis of acceptor-π-bridge-donor- π-bridge-acceptor (A-π-D-π-A) electron donor molecules. Based on the known benzodithiophene-terthiophene-rhodanine (BTR) material, th...

Journal: :The Journal of General Physiology 1980
S. Nakajima A. Gilai

Isolated single (Xenopus) muscle fibers were stained with a non-permeant potential-probing dye, merocyanine rhodanine (WW375) or merocyanine oxazolone (NK2367). When the fiber was massively stimulated, an absorption change (wave a), which seemed to reflect the action potential, occurred. Simultaneous recording of optical changes and intracellular action potentials revealed that the time-course ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Mike C Wolf Alexander N Freiberg Tinghu Zhang Zeynep Akyol-Ataman Andrew Grock Patrick W Hong Jianrong Li Natalya F Watson Angela Q Fang Hector C Aguilar Matteo Porotto Anna N Honko Robert Damoiseaux John P Miller Sara E Woodson Steven Chantasirivisal Vanessa Fontanes Oscar A Negrete Paul Krogstad Asim Dasgupta Anne Moscona Lisa E Hensley Sean P Whelan Kym F Faull Michael R Holbrook Michael E Jung Benhur Lee

We describe an antiviral small molecule, LJ001, effective against numerous enveloped viruses including Influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1. In sharp contrast, the compound had no effect on the infection of nonenveloped viruses. In vitro and in vivo assays showed no overt toxicity. LJ001 specifically intercalated into viral m...

Journal: :Plant physiology 1984
D T Manning T M Chen A J Campbell N E Tolbert E W Smith

The effects of various chemical treatments upon photosynthesis, soluble leaf protein, CO(2) compensation point, and leaf light transmission in soybean, Glycine max (L.) Merr., seedlings were examined following varying response periods after application at 14 to 17 days postemergence. The compounds N(6)-benzyladenine (BA), 2-(4-chlorophenoxy)-2-methylpropanoic acid (CPMP), (4-chlorophenoxy)aceti...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1995
K Sato Y Momose-Sato T Sakai A Hirota K Kamino

In an effort to assess the spatial patterning of glossopharyngeal responses in the early embryonic chick brainstem, we used a multiple-site optical recording system with a 12 x 12 element photodiode array and a voltage-sensitive merocyanine-rhodanine dye (NK2761) to monitor neural transmembrane voltage activities. Seven and 8 d old embryonic chick brainstems were sliced into 1400-1600 microns t...

Journal: :Physical chemistry chemical physics : PCCP 2015
Venkatesan Srinivasan Murugesan Panneer Madhavan Jaccob Nagaraj Pavithra Sambandam Anandan Arunkumar Kathiravan

An electron rich donor moiety plays an important role in dye sensitized solar cells (DSCs). In order to attain a suitable donor moiety for DSCs, a deeper understanding of the role of a donor moiety in the dye excited state is significant. In this context, different arylamine dye-based electron donor moieties (TRA, CRA and PyRA) were successfully synthesized and well characterized using (1)H-NMR...

Journal: :Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2012
Guo-Yu Jiang Wan-Hua Lei Qian-Xiong Zhou Yuan-Jun Hou Xue-Song Wang

Two 5,10,15,20-tetraphenylporphyrins with one phenyl group anchored to a rhodanine-terminated side chain, RhD-TPP and RhDCOOH-TPP, were designed and synthesized, and their protein photocleavage activities were investigated using bovine serum albumin (BSA) as a model protein. Both porphyrins exhibit similar absorption spectra, fluorescence spectra, fluorescence quantum yields, and singlet oxygen...

2014
William Sinko Yang Wang Wei Zhu Yonghui Zhang Ferran Feixas Courtney L. Cox Douglas A. Mitchell Eric Oldfield J. Andrew McCammon

There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin target bacterial cell wall biosynthesis, but methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) have now arisen and are of major concern. Inhibitors acting on new targets in cell wall biosynthesis are thus of particular interest ...

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