OBJECTIVES To describe a normal heart left bundle branch block, inferior axis ventricular tachycardia (VT), that could not be ablated from the right or left ventricular outflow tracts. BACKGROUND Whether these VTs are epicardial and can be identified by a specific electrocardiographic pattern is unclear. METHODS Twelve patients with normal heart left bundle branch block, inferior axis VT an...

BACKGROUND Connexin (Cx)40 and Cx45 are the major protein subunits of gap junction channels in the conduction system of mammals. To determine the role of Cx40, we correlated cardiac activation with Connexin distribution in normal and Cx40-deficient mice hearts. METHODS AND RESULTS Epicardial and septal activation was recorded in Langendorff-perfused adult mice hearts with a 247-point compound...

The phase image generated by radionuclide angiocardiography illustrates the regional timing of ventricular wall motion. In this study the phase image was used to investigate the patterns of ventricular contraction in 103 subjects with either normal hearts or a conduction abnormality. In 38 normal subjects the right ventricle contracted on average 7 ms after the left, and the last region to cont...

A 61 year old man developed acute pulmonary embolism while in hospital. His previous and admission electrocardiograms (ECGs) showed a typical left bundle branch block (LBBB) pattern. Immediately after the onset of acute pulmonary embolism, LBBB disappeared from his body surface ECG with sinus bradycardia, normalisation of QRS duration, prolonged QT interval, and marked T abnormalities to the ri...

A phonocardiographic study in a medium frequency range was made over various areas of the precordium in 27 cases of right bundle branch block (RBBB), 28 cases of left bundle branch block (LBBB), and 30 normal subjects of the same age. The various components of the first heart sound plus the pulses at the suprasternal notch and the right carotid artery were studied in regard to timing, relations...

Vectorcardiogram (VCG) recorded by both the Frank and Kimura systems were examined in 45 patients with complete right bundle branch block (RBBB) and left axis deviation (LAD) to investigate the relationship seen on electrocardiogram (ECG) between RBBB with LAD and bilateral bundle. The sample included: 13 cases of type SI, SII, SIII, SaVF; 21 cases of type SI, SII, SIII, aVF; and 11 cases of ty...