نتایج جستجو برای: riluzole

تعداد نتایج: 631  

Journal: :Acta Crystallographica Section A Foundations and Advances 2017

Journal: :The Journal of Thoracic and Cardiovascular Surgery 1999

Journal: :Journal of neurology, neurosurgery, and psychiatry 2016
Julie Labra Parvathi Menon Karen Byth Shea Morrison Steve Vucic

OBJECTIVE To assess the utility of rate of disease progression (ΔFS) as a prognostic biomarker in amyotrophic laterals sclerosis (ALS). METHODS A total of 203 patients with ALS were prospectively recruited over a 10-year period. At initial visit, the following variables were collected: demographic details, symptom duration, site of onset, phenotype, riluzole use and Amyotrophic Lateral Sclero...

Journal: :Journal of Clinical Pharmacy and Therapeutics 1996

2013
Elsa Fritz Pamela Izaurieta Alexandra Weiss Franco R. Mir David Gonzalez Fabiola Rojas Robert H. Brown Rodolfo Madrid

42 Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by dysfunction 43 and degeneration of motor neurons starting in adulthood. Recent studies using cell or animal 44 models document that astrocytes expressing disease-causing mutations of human 45 superoxide dismutase 1 (hSOD1) contribute to the pathogenesis of ALS by releasing a 46 neurotoxic factor(s). Neither the...

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