نتایج جستجو برای: rms
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Patients with metastatic rhabdomyosarcoma (RMS) have a poor prognosis. The detection of contaminating RMS cells in the bone marrow (BM) is important in clinical staging and risk assessment. The cytological examination of the BM remains the gold standard for the diagnosis of RMS, but has a limited sensitivity. In the present study, 32 BM and two cerebrospinal fluid (CSF) samples from 11 patients...
PURPOSE Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma and includes a PAX3- or PAX7-FOXO1 fusion-positive subtype. Amplification of chromosomal region 12q13-q14, which contains the CDK4 proto-oncogene, was identified in an aggressive subset of fusion-positive RMS. CDK4/6 inhibitors have antiproliferative activity in CDK4-amplified liposarcoma and neuroblastoma, suggesti...
CONTEXT Clinical studies have supported the efficacy of a variety of osteopathic manipulative techniques. However, an evidence base for the cellular mechanisms underlying these clinical findings is lacking. OBJECTIVE To investigate human fibroblast proliferation and interleukin secretory profiles in response to modeled repetitive motion strain (RMS) and modeled indirect osteopathic manipulati...
A Região Metropolitana de Sobral (RMS) foi a terceira região metropolitana institucionalizada no Estado do Ceará, em dezembro 2016. Em 2018, apresentado o relatório final Plano Desenvolvimento Urbano Integrado (PDUI), trazendo as diretrizes para desenvolvimento urbano e regional da unidade territorial. RMS é composta por 18 municípios, sendo cidade sua sede metropolitana, além ser considerada u...
Characterized reference materials (RMs) are needed for clinical laboratory test development and validation, quality control procedures, and proficiency testing to assure their quality. In this article, we review the development and characterization of RMs for clinical molecular genetic tests. We describe various types of RMs and how to access and utilize them, especially focusing on the Genetic...
Small businesses occupy a signifi cant role in policy debates. This paper reviews evidence relating to tax policy, small businesses, innovation, and entrepreneurship. We provide background information on the small business sector and alternative business defi nitions. We examine evidence suggesting that job growth and innovation tends to occur in young fi rms, which typically start off small, r...
The majority of U. S. temporary help supply (THS) rms offer nominally free, unrestricted computer skills training, a practice inconsistent with the competitive model of training. I propose and test a model in which rms offer general training to induce self-selection and perform screening of worker ability. The model implies, and the data conrm, that rms providing training attract higher abi...
Rhabdomyosarcoma (RMS) is a high-grade, malignant mesenchymal neoplasm. These tumors represent the most common soft tissue sarcomas of children and adolescents. RMS is uncommon on the lip and it is rarely seen in adults. Here, we report a rare case of primary RMS, embryonal type, occurring on the upper lip in a 27-year-old female.
An international project developed, quality-tested, and determined isotope-δ values of 19 new organic reference materials (RMs) for hydrogen, carbon, and nitrogen stable isotope-ratio measurements, in addition to analyzing pre-existing RMs NBS 22 (oil), IAEA-CH-7 (polyethylene foil), and IAEA-600 (caffeine). These new RMs enable users to normalize measurements of samples to isotope-δ scales. Th...
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