Neuro-oxidative-nitrosative stress may prove the molecular basis underlying brain dysfunction in sepsis. In the current review, we describe how sepsis-induced reactive oxygen and nitrogen species (ROS/RNS) trigger lipid peroxidation chain reactions throughout the cerebrovasculature and surrounding brain parenchyma, due to failure of the local antioxidant systems. ROS/RNS cause structural membra...

INTRODUCTION Several studies have shown a significant amplitude decrement in compound muscle action potentials (CMAPs) on repetitive nerve stimulation (RNS) of muscles involved in amyotrophic lateral sclerosis (ALS). In ALS, muscle wasting preferentially affects the thenar muscles (APB) rather than the hypothenar muscles (ADM). METHODS We performed RNS studies in the APB and ADM muscles of 32...

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced, in part, from NADPH oxidase in response to host invasion and tissue injury. Defects in NADPH oxidase impair host defense; however, the role of ROS and RNS in the response to tissue injury is not known. We addressed this issue by subjecting leukocyte oxidase (Nox2)-deficient (Nox2-/-) mice to arterial injury. Femoral...

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) targeting mitochondria are major causative factors in disease pathogenesis. The mitochondrial permeability transition pore (PTP) is a mega-channel modulated by calcium and ROS/RNS modifications and it has been described to play a crucial role in many pathophysiological events since prolonged channel opening causes cell death. The...

Residue Number Systems (RNS) are naturally considered as an interesting candidate to provide efficient arithmetic for implementations of cryptosystems such as RSA, ECC (Elliptic Curve Cryptography), pairings, etc. More recently, RNS have been used to accelerate fully homomorphic encryption as lattice-based cryptogaphy. In this paper, we present an RNS algorithm resolving the Closest Vector Prob...

As one of the processor's ALU performance issues, the carry propagation during the addition operation limits the speed of arithmetic operation. This work aims to build an Efficient Hardware Design for an Adder based on Residual Numbering System (RNS), with a pre-specified special set of moduli to simplify the implementation for the purpose of proving the feasibility of its usage. Our design can...

The objective of this study was to assess the effect of four different nurse staffing strategies on hospital costs: Part-time RNs; RN temporary agencies; RN rich skill mix; and organizationally experienced RNs. Two regression equations were specified to consider the effect of these strategies on personnel and benefit costs and on non-personnel operating costs. A number of additional variables w...

On an embedded device, an implementation of cryptographic operation, like an RSA modular exponentiation [12], can be attacked by side channel analysis. In particular, recent improvements on horizontal power analysis [3,10] render ineffective the usual counter-measures which randomize the data at the very beginning of the computations [4,2]. To counteract horizontal analysis it is necessary to r...

Providing regional projections of the RN workforce will allow underlying differences in the age structure of the RN workforce to become more visible. By providing regional-level projections, it will also be possible to identify those regions whose RN workforce is expected to grow at a slower rate relative to other regions. States in the South and Midwest have a greater supply of younger-aged RN...

This paper presents a novel architecture for a Residue Number System (RNS) based 1D 5/3 Discrete Wavelet Transform (DWT) implementation by using a combination of Filter Bank (FB) and Lifting Scheme (LS). It is designed to modify the architecture of existing binary lifting scheme based 5/3 DWT and RNS based Filter Bank (FB) 5/3 DWT. In this proposed architecture, non-binary RNS arithmetic operat...