AIM To investigate the effects of mammalian homologue of Drosophila diaphanous-1(mDia1) and Rho-associated coiled-coil-containing protein kinase (ROCK) on the migration and adhesion of dental pulp cells (DPCs). METHODOLOGY Lysophosphatidic acid (LPA) was used to activate Rho signalling. mDia1 and ROCK were inhibited by short interfering RNA and the specific inhibitor, Y-27632, respectively. T...

Shroom (Shrm) proteins are essential regulators of cell shape and tissue morpho-logy during animal development that function by interacting directly with the coiled-coil region of Rho kinase (Rock). The Shrm-Rock interaction is sufficient to direct Rock subcellular localization and the subsequent assembly of contractile actomyosin networks in defined subcellular locales. However, it is unclear ...

The dielectric constant of a partially saturated sandstone varies as a function of the level of water saturation. Experimental data indicate that rock/water interaction, at low saturations, has a large effect on the measured dielectric response. To theoretically predict the dielectric constant of the rock/water/air system, this rock/water interaction must be accounted for by including the effec...

Carving rock by indenting sharp objects into the surface under an impact force has been a favored method of fragmentation for millenia . However, as rock gets harder the lifetime of these sharp tools becomes short and, in a compromise hardened bits of rounder contour have become more common, particularly when driven by mechanical power. To better understand the behavior of these newer generatio...

Disease in Immunocompromised Hosts: A case-Control Study Senu Apewokin, MD; Aasiya Matin, MD; Naveen Sanath Kumar, MD; Shebli Atrash, MD; Bakhous Aziz; Jameel Muzaffar; Vyjayanthi Ganga, MD; Monica Grazziutti, MD; Medicine, University Of Arkansas For Medical Sciences, Little Rock, AR; Myeloma Institute or Research and Therapy, UNIVERSTIY OF ARKANSAS FOR MEDICAL SCIENCES, LITTLE ROCK, AR; The My...

BACKGROUND The Rho kinase pathway plays a key role in many early cell/tissue determination events that take place in embryogenesis. Rho and its downstream effector Rho kinase (ROCK) play pivotal roles in cell migration, apoptosis (membrane blebbing), cell proliferation/cell cycle, cell-cell adhesion and gene regulation. We and others have previously demonstrated that inhibition of ROCK blocks e...

Rock bolts ensure structural stability for tunnels and many other underground structures. The pre-load on a rock bolt plays an important role in the structural reinforcement and it is vital to monitor the pre-load status of rock bolts. In this paper, a rock bolt pre-load monitoring method based on the piezoceramic enabled time reversal method is proposed. A lead zirconate titanate (PZT) patch t...

OBJECTIVE It has been reported that leukocyte ROCK activity is elevated in patients after ischemic stroke, but it is unclear whether leukocyte ROCK activity is associated with clinical outcomes following acute stroke events. The objective of this study is to investigate if leukocyte ROCK activity can predict the outcomes in patients with acute ischemic stroke. MATERIALS AND METHODS We enrolle...

The paper presents summary of the work carried out by the author on the modelling of jointed rock mass with some field applications. The equivalent continuum analyses approach presented attempts to use statistical relations, which are simple and obtained after analyzing a large data from the literature on laboratory test results of jointed rock masses. Systematic investigations were done includ...

The prediction of rock mass behavior is an important task in many engineering projects, as the behavior of rock masses can be controlled by the presence of discontinuities. Being able to map the structure of a rock mass is crucial to understanding its potential behavior. This understanding can positively impact the safety and efficiency of an engineering project. In this research, rock masses w...