TRPC3 Mediates Hyperexcitability and Epileptiform Activity in Immature Cortex and 1 Experimental Cortical Dysplasia 2 3 Fu-Wen Zhou*, and Steven N. Roper 4 Departments of Neurosurgery and the McKnight Brain Institute, 5 University of Florida 6 7 Running Head: TRPC3 in cortical dysplasia 8 9 10 *Corresponding Author: 11 Fu-Wen Zhou, M.D., Ph.D. 12 Department of Neurosurgery 13 University of Flor...

In recent years, the U.S. Supreme Court has created two categorical exemptions to the death penalty. In Atkins v. Virginia, the Court exempted mentally retarded offenders. Three years later, in Roper v. Simmons, the Court extended the protection to juveniles. Based on these cases, the practices of foreign countries, and the opinions of professional organizations with relevant expertise, legal s...

The removal of metallic foreign bodies from various parts of the body is part of the daily work load of the accident and emergency department. Localization prior to removal is aided by X-rays with markers or image intensification. An alternative method involves the use of a metal locator. Metal locators have been used extensively in the removal of intraocular foreign bodies (Bronson & Turner, 1...

tion in fresh and paraffin-embedded tissue. Clin Chem. 1999;45:573574. 6. Butensky E, Fischer R, Hudes M, et al. Variability in hepatic iron concentration from percutaneous needle biopsy specimens in patients with transfusional hemosiderosis. Am J Clin Path. 2005;123:146-152. 7. Fischer R, Piga A, Harmatz P, Nielsen P. Monitoring long-term efficacy of iron chelation treatment with biomagnetic l...

We propose that the recently discovered Θ(1540) baryon is a bound state of four quarks and an antiquark, containing two highly correlated ud-pairs. If so, the Θ(1540) has positive parity, and it lies in an near-ideally mixed SU(3)f 10f ⊕8f . The Roper resonance and the P11(1710) fit naturally into this classification. We predict an isospin 3/2 multiplet of Ξ’s (S = −2) with J = 1 2 + around 175...

We consider decays of the lowest-lying radially excited baryons. Assuming a single-quark decay approximation , and negligible configuration mixing, we make model-independent predictions for the partial decay widths to final states with a single meson. Masses of unobserved states are predicted using an old mass formula rederived using large-Nc QCD. The momentum dependence of the one-body decay a...

We should like to thank Dr R. Y. Thomson and Mr R. Logan for their assistance in some of these experiments, Mr A. J. Taylor for technical assistance and Dr J. A. Roper of the Department of Genetics in this University for help in the radiation experiments. We are also indebted to Dr A. C. White of the Wellcome Physiology Research Laboratories for assistance in the supply of venom. The expenses o...