1. Assay of some photosynthetic bacteria for vitamin B(12) showed them to be relatively rich in this factor. Rhodopseudomonas spheroides, grown photosynthetically in Co(2+)-supplemented medium, contained about 100mug./g. dry wt. 2. Extracts of wild-type Rps. spheroides methylated homocysteine by a mechanism similar to the cobalamin-dependent pathway present in Escherichia coli. However, no mech...

PURPOSE Research shows that parenting factors and individual difference variables, such as sensation seeking (SS) and risk perceptions (RPs), are associated with increased motor vehicle crash risk for young drivers. The presence of peer passengers is also known to be associated with increased crash risk. However, as previous studies did not study these factors concurrently, less is known about ...

BACKGROUND Because retroperitoneal soft tissue sarcomas (RPS) are extremely rare, there is a significant lack of clinicopathologic information to optimize the treatment strategy. The aim of this study was to evaluate the prognostic factors in RPS, with particular focus on the Ki-67 labeling index (LI). METHODS We included the data from a total of 23 patients who received treatment for primary...

Protein synthesis is globally regulated through posttranslational modifications of initiation and elongation factors. Recent high-throughput studies have identified translation factors and ribosomal proteins (RPs) as substrates for the O-GlcNAc modification. Here we determine the extent and abundance of O-GlcNAcylated proteins in translational preparations. O-GlcNAc is present on many proteins ...

The capacity to inhibit a planned action gives human behavior its characteristic flexibility. How this mechanism operates and what factors influence a decision to act or not act remain relatively unexplored. We used EEG readiness potentials (RPs) to examine preparatory activity before each action of an ongoing sequence, in which one action was occasionally omitted. We compared RPs between seque...

BACKGROUND Although disease management programs for patients hospitalized with heart failure (HF) are effective, they are, however, often resource intensive, limiting their uptake. Peer support programs have led to improved outcomes among patients with other chronic conditions and may result in similar improvements for patients with HF. METHODS AND RESULTS In this randomized controlled trial,...

The resting membrane potential (RP) of vascular smooth muscle cells (VSMCs) is a major determinant of cytosolic calcium concentration and vascular tone. The heterogeneity of RPs and its underlying mechanism among different vascular beds remain poorly understood. We compared the RPs and vasomotion properties between the guinea pig spiral modiolar artery (SMA), brain arterioles (BA) and mesenteri...

Safety [1] is an important property for nuclear power plants in order to obtain permission from government authorities for their operation and possible export of power plant construction technology. As the nuclear reactor protection system (RPS) makes decisions for emergent reactor shutdown, RPS software should be verified throughout the entire software development life cycle (SDLC). Recent com...

The progression of many solid tumors is characterized by the release of tumor-associated proteases, such as cancer procoagulant, MMP2 and MMP7. Consequently, the detection of tumor-specific proteolytic activity in serum specimens has recently been proposed as a new diagnostic tool in oncology. However, tumor-associated proteases are highly diluted in serum specimens and it is challenging to ide...