This report presents the layered protocol stack of the WINNER wireless system, and describes the system functions associated with the IP Convergence Layer (IPCL), the Radio Resource Control (RRC). The document provides a consolidated description of the system functions associated to the IPCL and RRC layers of the WINNER system concept. An innovative and hybrid and scalable approach is proposed ...

In order to improve the wireless network performance, one of the most potential solutions is the use of a number of small size cells called femtocells. One of the facilitating technologies for LTE/ LTE-A (Long Term EvolutionAdvance) is the deployment of femtocellular network. As the number of femtocell increases, managing the radio resource becomes challenging due to the co existence of other f...

The sequence-specific RNA-binding proteins SRp20 and 9G8 are the smallest members of the serine- and arginine-rich (SR) protein family, well known for their role in splicing. They also play a role in mRNA export, in particular of histone mRNAs. We present the solution structures of the free 9G8 and SRp20 RNA recognition motifs (RRMs) and of SRp20 RRM in complex with the RNA sequence 5'CAUC3'. T...

Mutations in the components of the minor spliceosome underlie several human diseases. A subset of patients with isolated growth hormone deficiency (IGHD) harbors mutations in the RNPC3 gene, which encodes the minor spliceosome-specific U11/U12-65K protein. Although a previous study showed that IGHD patient cells have defects in U12-type intron recognition, the biochemical effects of these mutat...

In this paper we use Generalized Stochastic Petri Nets (GSPNs) and Stochastic Well-formed Nets (SWNs) for the performance analysis of Asynchronous Transfer Mode (ATM) Local Area Networks (LANs) that adopt the Available Bit Rate (ABR) service category in its Relative Rate Marking (RRM) version. We also consider a peculiar version of RRM ABR called Stop & Go ABR; this is a simplified ABR algorith...

RNA recognition motif (RRM) proteins represent an abundant class of proteins playing key roles in RNA biology. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 and SRSF1 complexes. The simulations are used in conjunction with NMR spectroscopy to interpret and expand the avail...

The usefulness of genetic progress for litter size in pig breeding is limited by mothering ability and piglets survival. It is a critical aspect for breeds used as dam lines, in which litter weight (LW) at weaning could be an alternative selection goal. Our objective was to investigate the genetic basis of LW at 21days for the six first parities in 1,449 Iberian sows with available records from...

The Mex67:Mtr2 complex is the principal yeast nuclear export factor for bulk mRNA and also contributes to ribosomal subunit export. Mex67 is a modular protein constructed from four domains (RRM, LRR, NTF2-like and UBA) that have been thought to be joined by flexible linkers like beads on a string, with the RRM and LRR domains binding RNAs and the NTF2-like and UBA domains binding FG-nucleoporin...

The main objective of next-generation wireless networks is to accommodate the increasing user demand and to achieve a ubiquitous high-data-rate coverage so that mobile broadband services comparable to those of the wirelines are realized in a costefficient manner. This ambitious objective however faces several technical challenges in the conventional cellular architecture, e.g., the large pathlo...

The regulation of gene expression in trypanosomatids occurs mainly at the post-transcriptional level. Despite the importance of this type of control in Trypanosoma cruzi, few RNA binding proteins have been characterized. The RRM domain (RNA Recognition Motif) is one of the most abundant domains found in RNA-binding proteins in higher eukaryotes. Proteins containing the RRM domain are involved i...