Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) rapidly spread worldwide. The exact mechanisms involved in the pathogenesis of Coronavirus Disease 2019 (COVID-19) are not fully understood. In addition to classical treatment, herbal medicine may effectively manage COVID-19 symptoms and supportive therapy. Scrophularia striata Boiss is a perennial herbaceous plant with immunomodulato...

Chemical analysis of the aqueous and n-butanol fractions methanolic extract Stipagrostis plumosa Munro ex T.Anderson, Poaceae, aerial parts led to isolation seven known phenolic glycosides 3,4′-dihydroxypropiophenone-3-O-β-d-glucoside, 5′-methoxy-3,4′-dihydroxypropiophenone-3-O-β-d-glucoside, 3′5′-dimethoxy-3,4′-dihydroxypropiophenone-3-O-β-d-glucoside, 3,4,5-trimethoxyphenyl-β-d-glucopyranose,...

Yerba mate (Ilex paraguariensis A.St. Hil) and jarilla (Larrea divaricata Cav.) leaves are commonly used as tea infusions in some Latin American countries. This study was conducted to evaluate the antioxidant activity (FRAP, ABTS, DPPH) inhibitory potential of yerba extracts on 3CL protease (Mpro) from coronavirus SARS-COV-2 by a molecular docking approach. The main bioactive compounds present ...

Kombucha is a renowned fermented drink for its diverse health benefits. This research aims to evaluate sweetened red ginger extract as an alternative substrate in making kombucha by observing the chemical properties (pH, total acid, sugar, polyphenol, compound profile using LC-MS/MS) and antioxidant activity. Three variables were varied, i.e., concentration (1, 5, 10%), culture (10 20%), fermen...

in the present study the volatile organic compounds of e. azerbaijanica rech.f. were identified. phytochemical assessment of meoh extract of aerial parts of this plant was also performed and its free radical scavenging properties was evaluated. the essential oil of the air-dried aerial parts was obtained by hydro-distillation using a clevenger type apparatus. the oil was then analyzed by gas ch...

Abstract A comparative metabolomic analysis was performed using purple potato tubers and derived red mutant to investigate the regulation of anthocyanin biosynthesis. The metabolome revealed 19 key differential metabolites including 10 flavonoids 4 nucleotides. As a metabolite, pelargonidin responsible for mutant, other had correlation with it. To further analyse regulatory mechanism metabolite...

Purpose: The aim of this study was to isolate and identify the active compound antioxidant fractions from Gardenia jasminoides Ellis leaves. Research Method: activity determined using DPPH 0.1 mM (1:1), analyzed spectrophotometrically. In addition, separation performed column chromatography. most identified by UV-Vis, FT-IR, LC-MS/MS. quantitative analysis done in three replicated. Findings: It...

Glucagon-like peptide-1 (GLP-1) is an incretin that is secreted from enteroendocrine L-cells. Dietary factor-stimulation of endogenous GLP-1 is a promising strategy for increasing the action of GLP-1. Recent studies have shown that berries rich in anthocyanins improve insulin sensitivity and reduce the risk of type 2 diabetes. Our previous study found that the anthocyanin delphinidin 3-rutinosi...

An anaerobic, quercetin-degrading bacterium was isolated from human feces and identified as Clostridium orbiscindens by comparative 16S rRNA gene sequence analysis. The organism was tested for its ability to transform several flavonoids. The isolated C. orbiscindens strain converted quercetin and taxifolin to 3,4-dihydroxyphenylacetic acid; luteolin and eriodictyol to 3-(3,4-dihydroxyphenyl)pro...