Normal salivary gland tissue has been recognized to positively stain for PSA, independently of gender, while immunostaining for AR has not been consistently found [6, 7]. Immunostaining for AR, and occasionally for prostatic acid phosphatase and PSA, has been reported in duct carcinoma and adenocarcinoma of salivary glands in both sexes [3–6, 8]. These findings suggest that, unlike prostate can...

a case of pleomorphic adenoma in sweat gland is reported here. the histopathologic report confirmed the diagnosis. pleomorphic adenoma is most common in salivary glands but very rare in sweat glands. pleomorphic adenoma in sweat gland and the similar tumors of eccring sweat gland are described that bear a striking resemblance to pleomorphic adenomas of salivary gland. upon closer examination, t...

Objective Fine-needle aspiration biopsy (FNAB) is widely used in the management of salivary gland masses. Its main advantage is its ability to differentiate benign from malignant disease. In this study, we aimed to evaluate the diagnostic ability of FNAB in salivary gland masses. Methods The records of patients who had undergone FNAB before parotidectomy or submandibular gland excision betwee...

Bone morphogenetic protein (BMP-6, also known as vegetal-pale-gene-related and decaplentaplegic-vegetal-related) is a member of the transforming growth factor-beta superfamily of multifunctional signaling molecules. BMP-6 appears to play various biological roles in developing tissues, including regulation of epithelial differentiation. To study the possible involvement of BMP-6 in normal and ne...

Background: Primary lymphoepithelial carcinoma (LEC) of salivary gland is a rare tumor with strong racial and geographical predilection among Eskimos and Orientals in Greenland and Asia, and with strong association with Epstein-Barr virus (EBV). So far, only about 4 cases of EBV negative LEC of salivary gland were reported in the non-endemic area in non-predilected ethnic groups in the English ...

PURPOSE To investigate the difference of expression of autophagy and reactive oxygen species (ROS) related proteins in adenoid cystic carcinoma (ACC) of lacrimal gland in comparison with ACC of salivary gland. MATERIALS AND METHODS Formalin-fixed, paraffin-embedded tissue samples from patients pathologically diagnosed as lacrimal gland ACC (n=11) and salivary gland ACC (n=64) were used. Immun...

CONTEXT AND OBJECTIVE Salivary gland tumor management requires long-term follow-up because of tumor indolence and possible late recurrence and distant metastasis. Adenoid cystic carcinoma (ACC) accounts for 10-15% of such tumors. The aim here was to evaluate surgical and clinical management, staging and follow-up of ACC patients in one academic institution. DESIGN AND SETTING Retrospective st...

Background. Renal cell carcinoma (RCC) metastasis to the salivary glands is extremely rare. Most cases reported previously have involved the parotid gland and only six cases involving the submandibular gland exist in the current literature. Metastasis of RCC to thyroid gland is also rare but appears to be more common than to salivary glands. Methods and Results. We present the first case of sim...

neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. submandibular gland tumors are relatively rare and...

introduction: high-dose radioactive iodine therapy in differentiated thyroid cancer (dtc) may adversely affect the salivary gland function. this study is aimed to evaluate the effect of radioactive iodine (rai) with dose of 100 mci in dtc patients compared to lower doses of less than 30 mci in hyperthyroid cases. methods: fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...