OBJECTIVE To detect immunohistochemically the N-cadherin expression in different types of benign and malignant salivary gland tumors in an attempt to note any possible correlation to their development, stage and invasive properties. MATERIALS AND METHODS N-cadherin expression was examined in tissue specimens from 49 salivary gland tumors including: pleomorphic adenomas (4), Warthin's tumors (...

The Drosophila embryonic salivary gland is a migrating tissue that undergoes a stereotypic pattern of migration into the embryo. We demonstrate that the migratory path of the salivary gland requires the PDGF/VEGF pathway. The PDGF/VEGF receptor, Pvr, is strongly expressed in the salivary glands, and Pvr mutations cause abnormal ventral curving of the glands, suggesting that Pvr is involved in g...

Malignant salivary gland tumours are rare. The most common tumour site is the parotid. Aetiologic factors are not clear. Nutrition may be a risk factor, as well as irradiation or an histologically benign tumour occurred at a young age. Painless swelling of a salivary gland should always be considered as suspicious, especially if no sign of inflammation is present. Signs and symptoms related to ...

The salivary glands are divided into major and minor/accessory glands. Tumours are not rare in salivary glands and are mainly found in major salivary glands. Tumours of accessory salivary glands are relatively less common. Accessory parotid gland is a small unit of salivary gland tissue lying on the masseter muscle and seperated from the main parotid gland with an accessory duct draining into t...

TO THE EDITOR: In their paper on salivary gland damage after high-dose radioiodine ablation therapy, Nakada et al. discuss an interesting and practical issue (1). The authors propose a radiation protection paradigm based on a concept of the dynamics of salivary gland function. The authors claim to have compared 2 radiation protection regimens in similar patients groups: a group that started suc...

(Received for publication, June 30, 1949) Since Bayliss and Bradford reported the electrical phenomena accom panied with secretory activity of animal salivary glands, a number of in vestigations have been made on this subject. A review is given in Har reveld's communication.1) As to the function of the human salivary gland, no investigation on action currents has appeared, because there is no m...