Lysozymes are ancient and important components of the innate immune system of animals that hydrolyze peptidoglycan, the major bacterial cell wall polymer. Bacteria engaging in commensal or pathogenic interactions with an animal host have evolved various strategies to evade this bactericidal enzyme, one recently proposed strategy being the production of lysozyme inhibitors. We here report the di...

BACKGROUND This report is about the investigation of an outbreak of typhoid fever claimed three human lives and left more than 300 people suffered within one week. The aim of this report is to draw the attention of global health community towards the areas that are still far from basic human essentialities. METHODS A total of 250 suspected cases of typhoid fever were interviewed, out of which...

The antibacterial activity of aqueous and ethanolic extracts of the seeds of Garcinia kola was investigated. Agar diffusion and paper disc methods were used for the investigation. The tested organisms: Staphylococcus aureus, Streptococcus pneumoniae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus epidermidis, Escherichia coli and Micrococcus luteus were obtained from the Molecula...

The antimicrobial effects of aqueous garlic extract (AGE) against 133 multidrug-resistant gram-positive and gram-negative bacterial isolates, including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Salmonella typhi, Pseudomonas aeruginosa, Escherichia coli, Shigella spp., and Proteus spp., and against 10 Candida spp....

Aims: To investigate Crude methanol extracts of 13 medicinal plants obtained through an ethnobotanical survey against 4 strains of mycobacteria (Mycobacterium tuberculosis, M. kansasii, M. fortuitum and M. smegmatis), Salmonella typhi, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumonia and Candida albicans. Materials and Methods: Antimycobacterial susceptibili...

Introduction: Litsea glutinosa (Lour.) c.B.rob., is an aromatic medicinal tree belongs to the family lauraceae and rarely distributed in the Western ghats. ethnomedicinally, the bark is used by the traditional practitioners as a demulcent, emollient and in the treatment of diarrhea and dysentery, and to facilitate wound healing process. the leaf paste is applied to relieve respiratory diseases;...

INTRODUCTION Bloodstream infections are associated with significant patient morbidity and mortality. Antimicrobial susceptibility patterns should guide the choice of empiric antimicrobial regimens for patients with bacteremia. METHODS Blood sample received from the patient attending Nepal Medical College and Teaching Hospital from March, 2012 - August, 2012 were subjected to culture. Isolate ...

A lectin isolated from the red alga Solieria filiformis was evaluated for its effect on the growth of 8 gram-negative and 3 gram-positive bacteria cultivated in liquid medium (three independent experiments/bacterium). The lectin (500 microg/mL) stimulated the growth of the gram-positive species Bacillus cereus and inhibited the growth of the gram-negative species Serratia marcescens, Salmonella...

Validation of a PCR test to detect hilA gene sequences of Salmonella spp. was performed in blood and faeces samples from typhoid fever and salmonellosis patients. Sensitivity (S), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV) of the PCR in blood samples were performed by testing: 37 patients with clinical diagnosis of typhoid fever, 34 of them confirmed b...

Some Vernonia species (Vernonia ambigua, Vernonia blumeoides and Vernonia oocephala) used in Northern Nigerian traditional medicine, were subjected to phytochemical screening using standard procedures. The antibacterial activity using the disc diffusion method as outlined by the NCCLS was carried out on Klebsiella pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Corynbacterium ulceran...