The Hha/YmoA family of nucleoid-associated proteins is involved in gene regulation in enterobacteria. In Salmonella enterica serovar Typhimurium, virulence genes required for intracellular growth are induced following host cell invasion but the proteins responsible for repressing these genes prior to host cell entry have not been fully identified. We demonstrate here that Hha is the major repre...

Consumption of contaminated poultry meat is still an important cause of Salmonella infections in humans and there is a need for control methods that protect broilers from day-of-hatch until slaughter age against infection with Salmonella. Colonisation-inhibition, a concept in which a live Salmonella strain is orally administered to day-old chickens and protects against subsequent challenge, can...

The interaction between schistosomiasis and Salmonella is a particularly important issue in Africa, where dual infection by the parasite and the bacterium are likely common. In this review, the ways in which schistosomiasis affects human biology as it relates to Salmonella are described. Those who are infected by both organisms experience reduced immunological functioning, exhibit irreversible ...

Intracellular pathogens must withstand nitric oxide (NO.) generated by host phagocytes. Salmonella enterica serovar Typhimurium interferes with intracellular trafficking of inducible nitric oxide synthase (iNOS) and possesses multiple systems to detoxify NO.. Consequently, the level of NO. stress encountered by S. Typhimurium during infection in vivo has been unknown. The Base Excision Repair (...

the genus of salmonella is very polymorphic and comprised of a number of genetically closely related serotypes. it is one of the emerging pathogen in food-borne disease which is often found in contaminated chicken eggs. salmonella enterica is considered one of the major pathogens in public health worldwide. a total of 31 salmonella isolates identified by specific antisera, which included salmon...

this experiment was conducted to compare the effects of multi-strain probiotic inclusion levels on performance, intestinal morphology, gut microflora and hematological changes in salmonella typhimurium (st) infected broiler chickens. a total of 120 day old ross 308 broiler chickens were distributed into 20 floor pens and reared for 10 days under 5 experimental treatments including a corn-soy ba...

background and aims: traditionally, plants have long been applied in the treatment of various diseases throughout the history of human life. the antimicrobial activity of plant extracts in the laboratory is studied on gram positive and negative strains of human infectious agents. the aim of this study was to evaluate the antibacterial activity of mentha longifolia against important human pathog...

conclusions the results indicated that dt increased anti-ops antibodies against the ops-dt compound. the antibody response to ops-dt was greater than that to ops alone. we conclude that ops-dt is an appropriate and acceptable vaccine candidate against salmonellosis. results two weeks after the first vaccination dose, there was no significant difference in the antibody titers of the ops and ops-...

Herein we reported the development of aptamer-based biosensors (aptasensors) based on label-free aptamers and gold nanoparticles (AuNPs) for detection of Escherichia coli (E. coli) O157:H7 and Salmonella typhimurium. Target bacteria binding aptamers are adsorbed on the surface of unmodified AuNPs to capture target bacteria, and the detection was accomplished by target bacteria-induced aggregati...

plasmids play an important role in the virulence and antibiotic resistance of salmonella. salmonella carry plasmids having different size and number. plasmid profile analysis of single isolates of salmonella typhimurium and salmonella enteritidis revealed the presence of 4- plasmid profiles. salmonella serovars produce several type iii secretions including sop-e and sop –b. soap e is detected b...