Sarcoidosis is a chronic systemic disease characterized by noncaseating granulomas. Thyroid involvement is rare, with a prevalence of 1-4% in large series of autopsied patients with systemic sarcoid. We report a case of a 65-year-old woman with a nontoxic multinodular goiter, dyspnea in the supine position, and rightward tracheal deviation as the initial presentation of systemic sarcoidosis. Fi...

Sarcoidosis is a multisystem inflammatory disorder of unknown etiology. It shows a great variety of clinical presentation, organ involvement, and disease progression. Lungs and lymphoid system are the most common sites involved with a frequency of 90% and 30%, respectively. Extrapulmonary involvement of sarcoidosis is reported in 30% of patients and abdomen is the most frequent site. Furthermor...

Sarcoidosis is a granulomatous inflammatory disorder of unclear etiology, which is known to affect multiple organ systems including the lungs, heart, skin, central nervous system, and eyes, among others. For this reason, sarcoidosis represents a systemic medical disorder that is clinically relevant to multiple medical sub-specialties. Despite extensive research, the etiology of sarcoidosis has ...

Sarcoidosis is a systemic granulomatous disorder of unknown etiology, characterized by chronic noncaseating epitheloid granulomatous inflammation with tissue destruction [1,2]. Renal involvement affects 20% of patients with sarcoidosis [1,2] and can be found in patients with no other localizations of the disease [3]. A common cause of renal dysfunction is hypercalcaemia and hypercalciuria leadi...

Heerfordt's syndrome is an unusual manifestation of sarcoidosis consisting of parotitis with chronic or subacute uveitis and often complicated by cranial nerve pareses, usually of the facial nerve. Originally described in 1909,1 it was not recognised as a manifestation of sarcoidosis until 1937. The complete picture is rare. Scadding2 had no cases of the complete syndrome in his series, and Gre...

In this article we present a 53-year-old lady, who had progressive indurated skin lesions on her both forearms since 3 months ago, without skin discoloration. Chest x-ray showed parahilar lymphadenopathy, in high resolution CT (HRCT) scan evaluation multiple lymph nodes in upper and middle mediastinum were reported. Angiotensin converting enzyme (ACE) level was increased to 81 (normal 5-5...

Sarcoidosis is a systemic disease mainly affecting the mediastinum and lungs. The other manifestations are much rarer lead to diagnostic therapeutic wanderings. present study reports case of lymph node sarcoidosis revealed by long-lasting fever. diagnosis based on clinical paraclinical arguments elimination causes lymphadenopathy. evolution favorable after 6 months corticosteroid therapy.

ciation between mycobacteria and sarcoidosis, and it has been hypothesized that sarcoidosis could be a separate manifestation of infection with mycobacteria. Therefore, most studies of a possible causal microoganism have focused on mycobacteria. Mycobacteria are ubiquitous all over the world with reservoirs in humans, animals, water and soil. Besides the usual forms, mycobacteria may exist in o...

Previous reports identified an association between sarcoidosis and an insertion/deletion (I/D) polymorphism in angiotensin-converting enzyme. Our meta-analysis of articles published between March 1996 and June 2013 identified studies in the PubMed, EMBASE, and the China National Knowledge Infrastructure databases. We examined whether angiotensin-converting enzyme polymorphisms influence sarcoid...

BACKGROUND Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Chronic cutaneous lupus erythematosus (CCLE) is an autoimmune disease that is associated with autoantibody production and T-cell dysfunction. Cutaneous manifestations of sarcoidosis may mimic CCLE and vice versa making it difficult to reach a diagnosis clinically. CASE PRESENTATION We present a case of a 57-yea...