Henoch-Schönlein purpura (HSP) is a systemic vasculitis involving the small vessels with distinct clinical features. The etiology of HSP is diverse, and viral infection is one of the many predisposing factors. Cytomegalovirus (CMV) infection mostly affects immune-suppressed patients, but rarely patients with normal immunity can also be affected. Authors experienced a case of HSP patient, with u...

An 81 year-old man presented to the emergency room with a history of fever, abdominal pain and bloody diarrhea. One week before his admission, he developed a skin rash on the lower extremities and buttocks and arthralgia in his knees and ankles. His medical history was unremarkable except for hypertension and a self-limited upper respiratory tract infection approximately one week before the ons...

11.1: Treatment of HSP nephritis in children 11.1.1: We suggest that children with HSP nephritis and persistent proteinuria, 40.5-1 g/d per 1.73 m, are treated with ACE-I or ARBs. (2D) 11.1.2: We suggest that children with persistent proteinuria, 41 g/d per 1.73 m, after a trial of ACE-I or ARBs, and GFR 450 ml/min per 1.73 m, be treated the same as for IgAN with a 6-month course of corticoster...

Henoch-Schönlein purpura (HSP) is the most common vasculitis in children. It is a disorder of the inflammatory cascade leading to immunoglobulin A deposition and leukocytoclastic vasculitis of small vessels of skin, kidneys, joints, and gastrointestinal (GI) tract. A wide variety of GI manifestations are seen in ∼50% to 75% of patients with HSP. Diffuse colicky abdominal pain is the most common...

Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis of childhood, affecting the small blood vessels. The disease is a clinical syndrome characterized by multiple organ involvement including the skin, joints, gastrointestinal tract, and the kidneys. Headache and behavioral changes can be frequently seen during the course of the disease, but severe neurological signs such as sei...

at a rate parallel to the clinical course of ARF. The high serum neopterin levels in our patients correlated well with Samsonov et al.'s results but increased urine neopterin levels in ARF were recorded in the literature. In conclusion, high neopterin concentrations indicate the activity of cellular immune system. An increase in neopterin concentrations supplies information on the activation st...

Henoch–Schö nlein purpura; IgA nephropathy; leuko-cytoclastic vasculitis; rapid progressive glomerulo-A 29-year-old patient sought medical advice in March nephritis; treatment 1998 for painful and swollen fingers. A week before hospital admission he had noticed progressive rash on the extremities, arthralgia of hips and shoulders and blue patches of skin on the dorsal fingers. He had a 10-year ...

Diagnosing HSP can be difficult, especially when abdominal symptoms precede the onset of characteristic palpable purpura (Chen MJ et al. 2005, World Gastroenterol., 11, 2354). Therefore, it is necessary to consider the possibility of HSP in patients with prolonged strong abdominal pain, even in cases without purpura.

Some reports have shown the association between Moyamoya syndrome and autoimmune diseases. Herewith, we present a 3.5 yr old girl with Henoch- Schönleinpurpura (HSP) who was treated with steroids because of sever colicky abdominal pain. However, central nervous system manifestations such as headache, ataxia and vision impairment developed during 6 months of her outpatient follow-up. More evalua...