Delivery of mental health services is changing world wide including India. Practice has shifted from an instrumental model of care to community based and family involvement based techniques. Despite that centrally, the views and experiences of family on the utility of the present classification system have been little studied. Present study was aimed to assess the difference of family pathology...

Linkage studies and epidemiological findings indicate that some possible genes in schizophrenia (SCZ) and bipolar mood disorder (BPD) are common. Numerous evidences for linkage of two diseases on chromosome 22 have been found. These findings suggest that one or more genes in the 22q11.21 region may be involved in the development of both disorders. In the present case-control study, association ...

BACKGROUND Common variants in the Vaccinia-related kinase 2 (VRK2) gene have been associated with schizophrenia, but the relevance of its encoded protein VRK2 in the disorder remains unclear. AIMS To identify potential differences in VRK2 gene expression levels between schizophrenia, bipolar disorder, psychosis not otherwise specified (PNOS) and healthy controls. METHOD VRK2 mRNA level was ...

BACKGROUND There is a need for better understanding and research of the comorbidity structure in schizophrenia and bipolar disorder. OBJECTIVE To assess the prevalence of somatic and psychiatric comorbidity in schizophrenia and bipolar affective disorder treated at the University Hospital Centre Zagreb. METHOD This retrospective study compares the prevalence of comorbid diagnosis of somatic...

INTRODUCTION Neuropsychological aspects of paranoid schizophrenia have still not been examined enough.These disorders are usually not studied separately, but are included in the studies about schizophrenic patients with positive symptoms. Despite the fact that schizophrenia represents a heterogeneous group of mental disorders, usually it is not separated from schizoaffective disorder in neurops...

The debate endures as to whether schizophrenia and bipolar disorder are separate entities or different manifestations of a single underlying pathological process. Here, we argue that this sterile argument obscures the fact that the truth lies somewhere in between. Thus, recent studies support a model whereby, on a background of some shared genetic liability for both disorders, patients with sch...

Childhood attentional and neuromotor precursors of social competence and affective deficits in adolescents at risk for schizophrenia, adolescents at risk for affective disorder, and matched comparison adolescents were examined. The subjects were offspring of parents with schizophrenia or affective disorder and of normal parents matched on age, sex, and socioeconomic status from the New York Hig...

Anomalous perception has been investigated extensively in schizophrenia, but it is unclear whether these impairments are specific to schizophrenia or extend to other psychotic disorders. Recent studies of visual context processing in schizophrenia (Tibber et al., 2013; Yang et al., 2013) point to circumscribed, task-specific abnormalities. Here we examined visual contextual processing across a ...

The impact of emotional arousal may be an equal or more important factor than valence in determining whether emotion interferes with language output in individuals with schizophrenia. An affective reactivity task, comprising conditions separated by emotional valence (positive, negative) and arousal (low, high), was administered to 22 individuals with schizophrenia or schizoaffective disorder an...