Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell...

Port community systems (PCS) are computer networks which link up the port with all the companies that use it, including haulers, rail companies, shipping lines, feeder ports, shippers and customs officers. Although these systems have promising benefits for the users, a lot of companies are reluctant to adopt them. Thus this paper tries to derive the factors that affect PCS adoption. For this pu...

Three known compounds including, uracil (1), 5-methyl (2) and uridine (3) have been isolated from the soft coral Litophyton arboreum collected red sea. The were identified using spectroscopic techniques predominately 1H-NMR 13C-NMR analyses, in addition to HR-ESI-MS. Moreover, 1-3 vitro estimated for their cytotoxic activity against three human cancer cell lines (A549, MCF-7 HepG2), antileishma...

5 Movement for many animal species is constrained in space by barriers such as rivers, shore6 lines, or impassable cliffs. We develop an approach for modeling animal movement con7 strained in space by considering a class of constrained stochastic processes, reflected stochas8 tic differential equations. Our approach generalizes existing methods for modeling uncon9 strained animal movement. We p...

Four new briarane diterpenoids, junceellolides M-P (1-4), were isolated together with seven known analogs (5-11) from the South China Sea gorgonian, Junceella gemmacea. The structures of these compounds were elucidated by detailed spectroscopic analysis and comparison with the reported data. The absolute configuration of compounds 1-3 were determined based on an ECD experiment, while the absolu...

Five new oxygenated pimarane diterpenes, named scopararanes C-G (1-5) were isolated from the culture of a marine sediment-derived fungus Eutypella scoparia FS26 obtained from the South China Sea. The structures of these compounds were established on the basis of extensive spectroscopic analysis. The absolute configurations of compounds 1-5, were determined by CD spectroscopic analysis and compa...

A subset of mRNAs, polyribosomes, and poly(A)-binding proteins copurify with microtubules from sea urchin embryos. Several lines of evidence indicate that the interaction of microtubules with ribosomes is specific: a distinct stalk-like structure appears to mediate their association; ribosomes bind to microtubules with a constant stoichiometry through several purification cycles; and the presen...

There was only a jigsaw puzzle of dry ground; A shroud of unfinished power lines dangling in silence. Shadow cows wandered over broken fence pieces, prodding memories of grass. I asked a hungry man, Where is the beautiful land I came to see? This is her legacy, he told me sadly. The legend you seek is dead. She was once virgin bride to the world. Her dowry was a sea of zebra. Her wildebeest thu...

Synthesis of mitotic spindle proteins is probably one of the normal preparations for division in higher cells (Mazia, 1961). Not so clear, however, is the situation in early embryonic development. The most widely accepted point of view, based upon several independent lines of evidence, is that the unfertilized egg contains a store of preformed spindle precursors, and that the controlling proces...

The sea cucumber (Holothuria atra) extracts have been evaluated for the presence of bioactive compounds and various biological activities. The methanol extracts showed anti proliferative activities against the Hela and MCF-7 cell lines. Similarly the inhibitory effects of Herpes simplex virus 1 and 2 cells were detected using the plaque reduction assay. The extracts of H. atra were purified usi...