Chronic renal failure leads to secondary hyperparathyroidism; the spontaneous evolution of this entity results in high bone remodelling. However, throughout the last decades we have learnt that several medical interventions, particularly those which involve a high degree of aluminium exposure, may change the evolution of secondary hyperparathyroidism, leading to other diseases such as aluminium...

A 55-year-old man was transferred to our hospital with unilateral lung lesions, a persistent fever and vague chest pain with arthralgia lasting for three months. He had been treated for end-stage renal disease with hemodialysis for 15 years and had a medical history of recurrent subcutaneous calciphylaxis due to secondary hyperparathyroidism. Transbronchial biopsied specimens demonstrated metas...

Multiple pathologic fractures secondary to parathyroid adenoma is rarely recognized and reported in the tropics. Inadequate evaluation causes worsened disability and increased psychological stress. We present a 27-year-old Nigerian male student with recurrent unexplained pathological fractures of the long bones. Primary Hyperparathyroidism was later diagnosed and he benefited from a unilateral ...

BACKGROUND Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease and treatment with vitamin D analogues is a mainstay of therapy. Although oral calcitriol and alfacalcidol are used extensively in Canada, there is little published data comparing equal doses of these agents. OBJECTIVES To compare the effect of equal doses of oral calcitriol and alfacalci...

Chronic kidney failure is much more common than people realize, and often goes undetected and undiagnosed until the disease is well advanced and k function decreases it affects many other systems of the body mainly the calcium phosphorous metabolism as the metabolism is mainly controlled by kidney in terms of absor of calcium phosphorus. Secondary hyperparathyroidism is usually found in patient...

Normocalcemic Primary Hyperparathyroidism (NC-PHPT) is a clinical entity characterized by normal serum calcium and persistently elevated parathyroid (PTH) levels. These patients have no obvious causes for secondary hyperparathyroidism such as vitamin D deficiency and renal insufficiency [1,2-16,17]. None of the patients had clear evidence of gastrointestinal disease. Although the entity NC-PHPT...

Secondary hyperparathyroidism is a common complication of end-stage renal disease (ESRD), which occurs as a result of hyperphosphataemia, hypovitaminosis D and hypocalcaemia. Chronic hyperparathyroidism can result in osteitis fibrosis cystica, also known as brown tumours. Spinal cord compression from a brown tumour is a rare emergency and of the eight reported cases in the literature, this repr...

Parathyroid glands produce parathyroid hormone (PTH). PTH has a main role in bone formation. Hyperparathyroidism (HPT) is explained as primary, secondary and tertiary types defined as overproduction of PTH. The brown tumor or osteitis fibrosa cystica is a benign bone lesion that is caused by HPT. This complication has been decreased by diagnosis and successful treatment of secondary hyperparath...

Metabolic syndrome is a cluster of metabolic abnormalities, including central obesity, insulin resistance, dyslipidemia, and hypertension. Parathyroid diseases are group disorders that affect the parathyroid glands’ function, which regulates body’s calcium phosphorus levels. There growing evidence may be associated with syndrome. body suggesting possible association between Hyperparathyroidism ...