background: secretory proteins of ige receptor activated mast cells and basophils play a pivotal role in the generation of immediate and long term immune responses in allergy and type i hypersensitivity. objective: the present study aims to generate a 2-d map and profile of proteins secreted from a high secretory variant of the rat basophilic leukemia cell line, rbl-2h3.1, which in view of the ...

BACKGROUND The clinical course of tuberculosis (TB) infection, bacterial load and the morphology of lesions vary between pulmonary and extrapulmonary TB. Antigens expressed in abundance during infection could represent relevant antigens in the development of diagnostic tools, but little is known about the in vivo expression of various M. tuberculosis antigens in different clinical manifestation...

Background. Trichinellosis is a parasitic zoonosis transmitted to humans by consumption of raw or undercooked meat from animals infected by worms of the Trichinella genus. Every year seropositive cases are found among the human population and thus trichinellosis still remains an epidemiologically important disease in Poland. The usefulness of ELISA for anti−T. spiralis IgG detection in pigs is ...

mucosal and glandular tissues, where they differentiate and Jean-Pierre Kraehenbuhl ‡ into plasma cells. The dimeric or polymeric IgA antibod-*Department of Pediatrics ies thus produced are selectively bound by epithelial Harvard Medical School and GI Cell Biology Laboratory polymeric immunoglobulin receptors, transcytosed Children's Hospital across epithelial cells, and released into glandular...

conclusions the current study indicated that the immunoreactivity of secretory iga might have no direct correlation with the colonization of indigenous flora and rejection of exogenous strains in adults. the relationship of microbes, host and dental caries should be in the light of coevolved microecosystem as a whole, but not caused by one factor alone. results the results showed that naturally...

Mucin glycoproteins are major secretory products of the colon and contain O-linked oligosaccharides synthesized on a polypeptide backbone. The initial step in the synthesis of O-linked oligosaccharides is the addition of N-acetylgalactosamine to serine or threonine residues forming the Tn antigen. This substance can then receive additional carbohydrate residues such as sialic acid to form sialo...

Background: Psoriasis is an immune mediated skin disorderwhich is mainly characterized by abnormal proliferation anddifferentiation of keratinocytes. It is believed that Debaryomyceshansenii (Candida famata) can colonize skin and mucous membranesof psoriatic patients and exacerbate psoriatic lesions via toxins,antigens, and proteins. The aims of this study were to evaluateDebaryomyces hansenii ...

The diagnosis of Chagas disease in humans is generally limited to the detection of specific antibodies. Detection of T. cruzi antigens in urine has been reported previously, but is not used in the diagnosis. In this study, soluble T. cruzi antigens and DNA were detected in urine samples and were associated with kidney injury and systemic detection of the parasite. We used 72 guinea pigs infecte...