Peculiar myelin figures were abundantly found in some basal-granulated cells including S, D1 and I cells in human Brunner's glands. Intense acid phosphatase activity was found in the periphery of the myelin figures, indicating that they were secondary lysosomes or residual bodies. The acid phosphatase activity was also found in some secretory granules. There were some secretory granules which w...

Ultrastructural differences in the tracheal gland between young and aged rats were studied. Marked differences were observed in the serous cells between the young (8-17 week-old) and the aged (20-30 month-old) subjects. The secretory granules of the serous cells of the young subjects were homogeneously electron dense, whilst those of the aged subjects had a bizonal appearance. These bizonal gra...

How neurosecretory cells spatially adjust their secretory vesicle pools to replenish those that have fused and released their hormonal content is currently unknown. Here we designed a novel set of image analyses to map the probability of tracked organelles undergoing a specific type of movement (free, caged or directed). We then applied our analysis to time-lapse z-stack confocal imaging of sec...

The present study aims at providing a detailed description of the histology, as well as the first histochemical characterization, of the secretory cells of the epidermis, pharynx, and copulatory organs of Choeradoplana iheringi, in order to give further support to studies on the physiology of these organs. The secretory cells are distinguished on the basis of secretion morphology and its staini...

Rho family GTPases are primary mediators of cytoskeletal reorganization, although they have also been reported to regulate cell secretion. Yet, the extent to which Rho family GTPases are activated by secretory stimuli in neural and neuroendocrine cells remains unknown. In bovine adrenal chromaffin cells, we found Rac1, but not Cdc42, to be rapidly and selectively activated by secretory stimuli ...

BACKGROUND There are four cell lineages derived from intestinal stem cells that are located at the crypt and villus in the mammalian intestine the non-secretory absorptive enterocytes, and the secretory cells, which include mucous-secreting goblet cells, regulatory peptide-secreting enteroendocrine cells and antimicrobial peptide-secreting Paneth cells. Although fibroblast growth factor (Fgf) s...

Adrenal chromaffin cells are typical paraneurons. They are of neural crest origin, secrete catecholamines and produce action potentials. In addition to adrenaline-storing (A) cells and noradrenaline-storing (NA) cells, a third calss of chromaffin cells is distinguishable. They are characterized by the smallness of the secretory granules, and hence are called small-granule chromaffin (SGC) cells...

background: inverse relationship between helminths infection and immune-mediated diseases has inspired researchers to investigate therapeutic potential of helminths in allergic asthma. helminth unique ability to induce immunoregulatory responses has already been documented in several experimental studies. this study was designed to investigate whether excretory/secretory (es) and somatic produc...