separation of ten sedative- hypnotic drugs was performed by rp-hplc using mixed micellar mobile phase. effect of temperature, type and amount of organic modifier in mobile phase on efficiency (n) and asymmetry factor (b/a) showed that, the appropriate conditions for a good separation were 35°c and 7% (v/v) butanol in mobile phase.  variations of selectivity factor versus butanol concentration, ...

to determine the neuropharmacological activity of the leaf extract of croton zambesicus in mice and chicks. the effect of aqueous leaf extract of croton zambesicus on thiopental sodium – induced sleeping time in mice, on gross locomotor activity (gla) in 2-day old chicks and effect of extract on apomorphine - induced stereotyped behavior in chicks were evaluated. the aqueous extract (1000 and 1...

General phytochemical screening of the aqueous extract of fruits of Solanum xanthocarpum (Solanaceae) revealed the presence of steroids, terpenes, phenolic compounds, saponins, fatty acids, alkaloids. Fractionation of aqueous extract and activity guided isolation resulted in isolation of two white crystalline powder which were subjected to physical, chemical and spectral identification using IR...

Glandular trichomes play important roles in protecting plants from biotic attack by producing defensive compounds. We investigated the metabolic profiles and transcriptomes to characterize the differences between different glandular trichome types in several domesticated and wild Solanum species: Solanum lycopersicum (glandular trichome types 1, 6, and 7), Solanum habrochaites (types 1, 4, and ...

This article reviews, connected the gap between the folkloric use of Solanum nigrum and the results of evidence based experiments. Although Solanum nigrum is a rich source of one of plants most dreaded toxins solanine, it has appreciably monstrated its potential as a reservoir of antioxidants having hepatoprotective, anti-tumor, cytostatic, anti-convulsant, anti-ulcerogenic and anti-inflammator...

A Solanum species long considered an American introduction to the Cape Verde Islands off the west coast of Africa is identified as Solanum rigidum, a member of the Eggplant clade of Old World spiny solanums (Solanum subgenus Leptostemonum) and is probably endemic to the Cape Verde Islands. Collections of this species from the Caribbean are likely to have been introduced from the Cape Verde Isla...

BACKGROUND Solanum nigrum fruit is traditionally used in Asia to manage, control, and treat diabetes but there is no scientific evidence of the efficacy of Solanum nigrum fruit in treatment of diabetes. We designed this study to investigate the effect of the administration of oral doses of aqueous extract from Solanum nigrum fruit on plasma glucose, lipid profiles, and the sensitivity of the va...