In order to extract neural information, action potentials recorded with cuff electrodes from peripheral nerves were classified into unit activities. The classification was performed based on their waveforms, as it was considered that they were affected by the radius of nerve fiber and the distance between fiber and recording electrode. This study focused on automatic classification method. Acti...

A previously published computer simulation was tested in a biological preparation by recording action potentials from frog sciatic nerves within a volume conductor filled with Ringer's solution. Traveling in a straight line, nerve action potentials traversed a constricted cylinder before crossing into a larger, hemicylindrical volume. Recordings from widely spaced electrodes in the larger volum...

In nerve cells, information is coded and transmitted as a series of electrical impulses called “action potentials,” which represent a brief change in cell electric potential. Nerve signals are frequency modulated; that is, the number of action potentials that occur in a unit of time is proportional to the intensity of the transmitted signal. An action potential can be elicited artificially by c...

INTRODUCTION The sural/radial nerve amplitude ratio (SRAR) is the quotient of the sensory nerve action potential (SNAP) amplitudes (Amp) of the sural and the superficial radial nerve. It has been hypothesized that this ratio can be used for the detection of early axonal loss, because the sural SNAP amplitude will decrease first, thereby also decreasing the SRAR value. OBJECTIVES To determine ...

A 9 year old boy had chronic progressive motor-sensory neuropathy that started in early infancy. He had enlarged nerves and pes cavus deformity. Motor conduction studies showed very dispersed, polyphasic compound muscle action potentials with conduction velocities around 2 m/s. A sural nerve biopsy showed severe loss of myelinated fibres. Two months of treatment with corticosteroids restored mu...